Estradiol

BCL2 apoptosis regulator ; Homo sapiens







51 Article(s)
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1 33484789 Fenhexamid induces cancer growth and survival via estrogen receptor-dependent and PI3K-dependent pathways in breast cancer models. 2021 Mar 1
2 34318539 Estradiol exerts a neuroprotective effect on SH-SY5Y cells through the miR-106b-5p/TXNIP axis. 2021 Sep 1
3 34951372 β-Estradiol Induces Mitochondrial Apoptosis in Cervical Cancer Through the Suppression of AKT/NF-κB Signaling Pathway. 2021 Dec 22 1
4 32621200 Zinc oxide nanoparticles enhance expression of maspin in human breast cancer cells. 2020 Oct 1
5 33745261 Genistein Induces Bcl-2 Expression in Human Dermal Microvascular Endothelial Cells: a Short Report. 2020 1
6 31189128 17β-Estradiol promotes endometrial cancer proliferation and invasion through IL-6 pathway. 2019 Jul 1
7 29686616 Estradiol Activates PI3K/Akt/GSK3 Pathway Under Chronic Neurodegenerative Conditions Triggered by Perinatal Asphyxia. 2018 1
8 25612679 Inhibition of Testosterone Aromatization by the Indole-3-carbinol Derivative CTet in CYP19A1-overexpressing MCF-7 Breast Cancer Cells. 2015 1
9 25791820 Synergistic anticancer potential of dichloroacetate and estradiol analogue exerting their effect via ROS-JNK-Bcl-2-mediated signalling pathways. 2015 1
10 26090392 Roles of ERβ and GPR30 in Proliferative Response of Human Bladder Cancer Cell to Estrogen. 2015 1
11 24552218 Apoptotic effects of high estradiol concentrations on endometrial glandular cells. 2014 Jun 1
12 25113166 The effects of steroid hormone exposure on direct gene regulation. 2014 Oct 1
13 23539633 Endometriosis: hormone regulation and clinical consequences of chemotaxis and apoptosis. 2013 Jul-Aug 1
14 22493348 Physiological concentrations of genistein and 17β-estradiol inhibit MDA-MB-231 breast cancer cell growth by increasing BAX/BCL-2 and reducing pERK1/2. 2012 Apr 2
15 21327582 17β-estradiol protects dopaminergic neurons in organotypic slice of mesencephalon by MAPK-mediated activation of anti-apoptosis gene BCL2. 2011 Oct 1
16 21469974 Effects of drospirenone/estradiol on steroid receptors and Bcl-2 in the postmenopausal endometrium. 2011 Oct 2
17 20340172 ER-β mediates 17β-estradiol attenuation of HIV-1 Tat-induced apoptotic signaling. 2010 Nov 1
18 20654613 The protective effect of 17beta-estradiol postconditioning against hypoxia/reoxygenation injury in human gastric epithelial cells. 2010 Oct 25 1
19 19264808 Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. 2009 May 2
20 19294490 Apoptotic effects of Tian-Long compound on endometrial adenocarcinoma cells in vitro. 2009 Mar 1
21 20141615 Oestrogen modulates human macrophage apoptosis via differential signalling through oestrogen receptor-alpha and beta. 2009 Aug 1
22 18652667 Conjugated linoleic acid induces apoptosis through estrogen receptor alpha in human breast tissue. 2008 Jul 24 1
23 17138646 MAPK signaling is critical to estradiol protection of CA1 neurons in global ischemia. 2007 Mar 2
24 17287517 Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death. 2007 Feb 7 2
25 17675494 Up-regulation of Bcl-2 through ERK phosphorylation is associated with human macrophage survival in an estrogen microenvironment. 2007 Aug 15 9
26 16538384 p38 Mitogen-activated protein kinases is required for counteraction of 2-methoxyestradiol to estradiol-stimulated cell proliferation and induction of apoptosis in ovarian carcinoma cells via phosphorylation Bcl-2. 2006 Mar 1
27 15909128 Down-regulation of Bcl-2 enhances estrogen apoptotic action in long-term estradiol-depleted ER(+) breast cancer cells. 2005 May 4
28 15001646 Estrogen receptor (ER)alpha and ER beta are both expressed in human ejaculated spermatozoa: evidence of their direct interaction with phosphatidylinositol-3-OH kinase/Akt pathway. 2004 Mar 1
29 12604781 Mechanism of estrogen-mediated neuroprotection: regulation of mitochondrial calcium and Bcl-2 expression. 2003 Mar 4 1
30 12740907 Antiestrogens are pro-apoptotic in normal human breast epithelial cells. 2003 Jul 10 1
31 14675202 17beta-estradiol inhibits oxidative stress-induced apoptosis in keratinocytes by promoting Bcl-2 expression. 2003 Dec 8
32 11237391 Anti-oestrogen resistant human breast cancer cell lines are more sensitive towards treatment with the vitamin D analogue EB1089 than parent MCF-7 cells. 2001 Mar 2 4
33 11356682 Estradiol up-regulates antiapoptotic Bcl-2 messenger ribonucleic acid and protein in tumorigenic ovarian surface epithelium cells. 2001 Jun 1
34 11391701 Nongenomic antiapoptotic signal transduction by estrogen in cultured cortical neurons. 2001 Jun 1 3
35 11606022 17-beta-estradiol alters Jurkat lymphocyte cell cycling and induces apoptosis through suppression of Bcl-2 and cyclin A. 2001 Oct 1
36 10733592 17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence. 2000 Apr 5
37 10870682 Influence of estrogen, antiestrogen and UV-light on the balance between proliferation and apoptosis in MCF-7 breast adenocarcinoma cells culture. 2000 1
38 11202219 Estradiol: a protective factor in the adult brain. 2000 1
39 11776601 [Effect of tamoxifen on apoptosis and drug resistance of breast cancer cells in vitro]. 2000 Jan 1
40 9886853 Androgens down-regulate bcl-2 protooncogene expression in ZR-75-1 human breast cancer cells. 1999 Jan 1
41 10403783 Differential membrane antioxidant effects of immediate and long-term estradiol treatment of MCF-7 breast cancer cells. 1999 Jul 5 3
42 10472781 Differential effects of chemotherapeutic agents on the Bcl-2/Bax apoptosis pathway in human breast cancer cell line MCF-7. 1999 May 1
43 10507761 Paradoxical regulation of Bcl-2 family proteins by 17beta-oestradiol in human breast cancer cells MCF-7. 1999 Oct 5
44 10537367 Tamoxifen-induced apoptosis in breast cancer cells relates to down-regulation of bcl-2, but not bax and bcl-X(L), without alteration of p53 protein levels. 1999 Oct 2
45 10542244 Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cells. 1999 Nov 5 2
46 11477803 [The regulation of estrogen and tamoxifen to bcl-2 oncogene in endometrial carcinoma]. 1999 Oct 2
47 9626159 Up-regulation by progesterone of proliferating cell nuclear antigen and epidermal growth factor expression in human uterine leiomyoma. 1998 Jun 2
48 8989276 Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone. 1997 Jan 1
49 9116321 Estrogen increases intracellular p26Bcl-2 to p21Bax ratios and inhibits taxol-induced apoptosis of human breast cancer MCF-7 cells. 1997 Jan 2
50 9470815 Short- and long-term oestradiol treatment inhibits growth and alters expression of p21WAF1/Cip1 in an endometrial adenocarcinoma cell line lacking functional p53. 1997 Nov 1