Acetylcysteine

BCL2 apoptosis regulator ; Homo sapiens







46 Article(s)
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1 33404763 Effects of N-acetyl cysteine on mitochondrial ROS, mitochondrial dynamics, and inflammation on lipopolysaccharide-treated human apical papilla cells. 2021 Jun 1
2 33880372 ROS-Triggered Autophagy Is Involved in PFOS-Induced Apoptosis of Human Embryo Liver L-02 Cells. 2021 1
3 34064109 Oxidative Stress-Induced Unscheduled CDK1-Cyclin B1 Activity Impairs ER-Mitochondria-Mediated Bioenergetic Metabolism. 2021 May 21 1
4 34156614 N-acetylcysteine ameliorate cytotoxic injury in piglets sertoli cells induced by zearalenone and deoxynivalenol. 2021 Nov 1
5 31995555 Application of non-invasive low-intensity pulsed electric field with thermal cycling-hyperthermia for synergistically enhanced anticancer effect of chlorogenic acid on PANC-1 cells. 2020 2
6 31524245 N‑acetyl cysteine inhibits lipopolysaccharide‑induced apoptosis of human umbilical vein endothelial cells via the p38MAPK signaling pathway. 2019 Sep 1
7 29679655 N-acetylcysteine transforms necrosis into apoptosis and affords tailored protection from cisplatin cytotoxicity. 2018 Jun 15 1
8 30603674 N-acetylcysteine protects hepatocytes from hypoxia-related cell injury. 2018 Dec 2
9 33817118 Emodin Promotes Apoptosis of Human Endometrial Cancer Through Regulating the MAPK and PI3K/ AKT Pathways. 2018 Jan 2
10 28380464 Heat stress induces intestinal injury through lysosome- and mitochondria-dependent pathway in vivo and in vitro. 2017 Jun 20 1
11 28399781 PCB 118-induced endothelial cell apoptosis is partially mediated by excessive ROS production. 2017 Jun 1
12 26809061 Nickel(II)-induced nasal epithelial toxicity and oxidative mitochondrial damage. 2016 Mar 1
13 27028622 Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. 2016 1
14 27785026 Amorphous silica nanoparticles trigger vascular endothelial cell injury through apoptosis and autophagy via reactive oxygen species-mediated MAPK/Bcl-2 and PI3K/Akt/mTOR signaling. 2016 1
15 25909282 Synergistic protection of N-acetylcysteine and ascorbic acid 2-phosphate on human mesenchymal stem cells against mitoptosis, necroptosis and apoptosis. 2015 Apr 24 1
16 24556569 Protective effects of N-acetylcysteine against monosodium glutamate-induced astrocytic cell death. 2014 May 1
17 24700345 Altholactone induces reactive oxygen species-mediated apoptosis in bladder cancer T24 cells through mitochondrial dysfunction, MAPK-p38 activation and Akt suppression. 2014 Jun 2
18 25202081 Equol induces mitochondria-mediated apoptosis of human cervical cancer cells. 2014 Sep 1
19 23292300 Apoptosis induction of human prostate carcinoma cells by cordycepin through reactive oxygen species‑mediated mitochondrial death pathway. 2013 Mar 1
20 23386420 N-acetyl-L-cysteine inhibits bleomycin induced apoptosis in malignant testicular germ cell tumors. 2013 Jul 1
21 23782641 Phaseoloideside E, a novel natural triterpenoid saponin identified from Entada phaseoloides, induces apoptosis in Ec-109 esophageal cancer cells through reactive oxygen species generation. 2013 1
22 24877026 Pristimerin Induces Apoptosis in Prostate Cancer Cells by Down-regulating Bcl-2 through ROS-dependent Ubiquitin-proteasomal Degradation Pathway. 2013 Nov 5 3
23 22245127 Nickel (II)-induced cytotoxicity and apoptosis in human proximal tubule cells through a ROS- and mitochondria-mediated pathway. 2012 Mar 1 1
24 22562160 Effects of N-acetylcystein on bleomycin-induced apoptosis in malignant testicular germ cell tumors. 2012 Dec 1
25 22824464 NG, a novel PABA/NO-based oleanolic acid derivative, induces human hepatoma cell apoptosis via a ROS/MAPK-dependent mitochondrial pathway. 2012 Sep 15 2
26 20868662 The cytotoxic mechanism of malondialdehyde and protective effect of carnosine via protein cross-linking/mitochondrial dysfunction/reactive oxygen species/MAPK pathway in neurons. 2011 Jan 10 1
27 21303669 Effects of lipoic acid on antiapoptotic genes in control and ethanol-treated fetal rhombencephalic neurons. 2011 Apr 6 1
28 21777666 Barakol-induced apoptosis in P19 cells through generation of reactive oxygen species and activation of caspase-9. 2011 Sep 2 1
29 20674558 1-(3',4',5'-Trimethoxyphenyl)-3-(3'',4''-dimethoxy-2''-hydroxyphenyl)-propane with microtubule-depolymerizing ability induces G2/M phase arrest and apoptosis in HepG2 cells. 2010 Oct 6 2
30 18323457 MSFTZ, a flavanone derivative, induces human hepatoma cell apoptosis via a reactive oxygen species- and caspase-dependent mitochondrial pathway. 2008 Jun 1
31 18512759 N-acetylcysteine prevents beta-amyloid toxicity by a stimulatory effect on p35/cyclin-dependent kinase 5 activity in cultured cortical neurons. 2008 Sep 2
32 18628592 Mitochondrial transmembrane potential and reactive oxygen species generation regulate the enhanced effect of CCCP on TRAIL-induced SNU-638 cell apoptosis. 2008 Jun 1
33 17542780 Morphine inhibits doxorubicin-induced reactive oxygen species generation and nuclear factor kappaB transcriptional activation in neuroblastoma SH-SY5Y cells. 2007 Sep 1 2
34 17760840 Caveolin and MAP kinase interaction in angiotensin II preconditioning of the myocardium. 2007 Jul-Aug 1
35 18077580 N-acetylcysteine attenuates arsenite-induced oxidative injury in dorsal root ganglion explants. 2007 Dec 1
36 15941563 Emodin induces apoptosis in human lung adenocarcinoma cells through a reactive oxygen species-dependent mitochondrial signaling pathway. 2005 Jul 15 1
37 15298726 Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. 2004 Aug 1
38 12754095 N-Acetylcysteine enhances UV-mediated caspase-3 activation, fragmentation of E2F-4, and apoptosis in human C8161 melanoma: inhibition by ectopic Bcl-2 expression. 2003 May 15 3
39 11820937 Cellular toxicity of cadmium ions and their detoxification by heavy metal-specific plant peptides, phytochelatins, expressed in Mammalian cells. 2002 Feb 1
40 10777712 The differential expression of apoptosis factors in the alveolar epithelium is redox sensitive and requires NF-kappaB (RelA)-selective targeting. 2000 Apr 29 1
41 10962206 Role of paxillin in metabolic oxidative stress-induced cytoskeletal reorganization: involvement of SAPK signal transduction pathway and PTP-PEST gene expression. 2000 Jul 1 1
42 11042671 Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells. 2000 Sep 1
43 9580328 Induction of apoptosis by vanilloid compounds does not require de novo gene transcription and activator protein 1 activity. 1998 Mar 1
44 9581775 NF-kappaB protects HIV-1-infected myeloid cells from apoptosis. 1998 Apr 25 2
45 9210957 Suppression of nitric oxide-induced apoptosis by N-acetyl-L-cysteine through modulation of glutathione, bcl-2, and bax protein levels. 1997 Jun 1
46 7739519 Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. 1995 May 1