Pub. Date : 2010 Oct 6
PMID : 20674558
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | DP increased the levels of reactive oxygen species (ROS) in HepG2 cells, and antioxidant N-acetylcysteine (NAC) completely blocked DP-induced ROS accumulation and the disruption of the balance between Bax and Bcl-2 proteins, and effectively blocked the decreased MMP and apoptosis, but had no effect on the activation of caspase-8 and the up-regulations of DR4 and DR5 induced by DP. | Acetylcysteine | BCL2 apoptosis regulator | Homo sapiens |
2 | DP increased the levels of reactive oxygen species (ROS) in HepG2 cells, and antioxidant N-acetylcysteine (NAC) completely blocked DP-induced ROS accumulation and the disruption of the balance between Bax and Bcl-2 proteins, and effectively blocked the decreased MMP and apoptosis, but had no effect on the activation of caspase-8 and the up-regulations of DR4 and DR5 induced by DP. | Acetylcysteine | BCL2 apoptosis regulator | Homo sapiens |