Sorafenib

BCL2 associated X, apoptosis regulator ; Homo sapiens







25 Article(s)
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1 35222709 Combination treatment with sorafenib and wh-4 additively suppresses the proliferation of liver cancer cells. 2022 Mar 1
2 35241510 Combination Treatment of Sorafenib and Bufalin Induces Apoptosis in NCI-H292 Human Lung Cancer Cells In Vitro. 2022 Mar-Apr 1
3 34076978 Long noncoding RNA NEAT1 aggravates sorafenib-resistance in non-small cell lung cancer via regulating miRNA-335/c-Met. 2021 Mar-Apr 1
4 29156516 Synergistic anticancer activity of 20(S)-Ginsenoside Rg3 and Sorafenib in hepatocellular carcinoma by modulating PTEN/Akt signaling pathway. 2018 Jan 1
5 29959200 Arsenic Trioxide and Sorafenib Induce Synthetic Lethality of FLT3-ITD Acute Myeloid Leukemia Cells. 2018 Sep 1
6 27632413 Sorafenib potentiates ABT-737-induced apoptosis in human oral cancer cells. 2017 Jan 2
7 27807662 C2-ceramide enhances sorafenib-induced caspase-dependent apoptosis via PI3K/AKT/mTOR and Erk signaling pathways in HCC cells. 2017 Feb 1
8 28154184 Bax/Bak-independent mitochondrial depolarization and reactive oxygen species induction by sorafenib overcome resistance to apoptosis in renal cell carcinoma. 2017 Apr 21 1
9 28476378 Upregulated expression of Nucleostemin/GNL3 is associated with poor prognosis and Sorafenib Resistance in Hepatocellular Carcinoma. 2017 Jun 1
10 27484637 Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy. 2016 Oct 1
11 25451688 Oncogenic c-Myc and prothymosin-alpha protect hepatocellular carcinoma cells against sorafenib-induced apoptosis. 2015 Jan 1 1
12 25683251 Activation of AMP-activated protein kinase by retinoic acid sensitizes hepatocellular carcinoma cells to apoptosis induced by sorafenib. 2015 May 1
13 24213303 Stimulatory effects of sorafenib on human non‑small cell lung cancer cells in vitro by regulating MAPK/ERK activation. 2014 Jan 1
14 24402682 ROS-mediated JNK/p38-MAPK activation regulates Bax translocation in Sorafenib-induced apoptosis of EBV-transformed B cells. 2014 Mar 1
15 24571452 ABT-263 enhances sorafenib-induced apoptosis associated with Akt activity and the expression of Bax and p21((CIP1/WAF1)) in human cancer cells. 2014 Jul 2
16 24989014 Differential combined effect of COX inhibitors on cell survival suppressed by sorafenib in the HepG2 cell line. 2014 1
17 25136776 Sorafenib regulating ERK signals pathway in gastric cancer cell. 2014 Sep 1
18 21604268 Sorafenib sensitizes hepatocellular carcinoma cells to physiological apoptotic stimuli. 2012 Apr 1
19 22446485 Inhibition of Bcl-2 antiapoptotic members by obatoclax potently enhances sorafenib-induced apoptosis in human myeloid leukemia cells through a Bim-dependent process. 2012 Jun 21 1
20 22689683 The sorafenib plus nutlin-3 combination promotes synergistic cytotoxicity in acute myeloid leukemic cells irrespectively of FLT3 and p53 status. 2012 Nov 1
21 20197401 Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. 2010 Mar 1
22 19366808 Sorafenib induces apoptosis specifically in cells expressing BCR/ABL by inhibiting its kinase activity to activate the intrinsic mitochondrial pathway. 2009 May 1 1
23 19483105 BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. 2009 Aug 2
24 18200035 Sorafenib induces apoptosis of AML cells via Bim-mediated activation of the intrinsic apoptotic pathway. 2008 Apr 2
25 18765530 Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation. 2008 Sep 1 1