Curcumin

BCL2 associated X, apoptosis regulator ; Homo sapiens







121 Article(s)
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51 25760477 Curcumin triggers apoptosis via upregulation of Bax/Bcl-2 ratio and caspase activation in SW872 human adipocytes. 2015 Jul 3
52 25789029 A preliminary study of the effect of curcumin on the expression of p53 protein in a human multiple myeloma cell line. 2015 Apr 1
53 25979368 Curcumin potentiates the anti-leukemia effects of imatinib by downregulation of the AKT/mTOR pathway and BCR/ABL gene expression in Ph+ acute lymphoblastic leukemia. 2015 Aug 1
54 26166196 Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway. 2015 Oct 1
55 26460892 Curcumin induces p53-independent necrosis in H1299 cells via a mitochondria-associated pathway. 2015 Nov 1
56 24318305 Potentiation of paclitaxel activity by curcumin in human breast cancer cell by modulating apoptosis and inhibiting EGFR signaling. 2014 Aug 1
57 24496855 PI3K/Akt pathway involving into apoptosis and invasion in human colon cancer cells LoVo. 2014 May 1
58 24604218 Induction of apoptosis by diphenyldifluoroketone in osteogenic sarcoma cells is associated with activation of caspases. 2014 May 2
59 24935585 Curcumin induces apoptosis in SGC-7901 gastric adenocarcinoma cells via regulation of mitochondrial signaling pathways. 2014 1
60 25338570 [Synergistic killing effect of arsenic trioxide combined with curcumin on KG1a cells]. 2014 Oct 1
61 22628241 Curcumin inhibits proliferation and induces apoptosis of human colorectal cancer cells by activating the mitochondria apoptotic pathway. 2013 Mar 1
62 23001851 Effects of curcumin on bleomycin-induced apoptosis in human malignant testicular germ cells. 2013 Jun 1
63 23219912 Curcumin attenuates endothelial cell oxidative stress injury through Notch signaling inhibition. 2013 Mar 1
64 23451189 Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-κB and Src protein kinase signaling pathways. 2013 1
65 23584140 Citrus limonoids and curcumin additively inhibit human colon cancer cells. 2013 Apr 30 1
66 23685957 Curcumin inhibits AP-2γ-induced apoptosis in the human malignant testicular germ cells in vitro. 2013 Sep 1
67 23760980 MicroRNA-200a/b influenced the therapeutic effects of curcumin in hepatocellular carcinoma (HCC) cells. 2013 Oct 1
68 23794119 Upregulation of extrinsic apoptotic pathway in curcumin-mediated antiproliferative effect on human pancreatic carcinogenesis. 2013 Dec 1
69 23802572 Curcumin induces apoptosis in gallbladder carcinoma cell line GBC-SD cells. 2013 Jun 26 1
70 23881281 Curcumin induces apoptosis in human gastric carcinoma AGS cells and colon carcinoma HT-29 cells through mitochondrial dysfunction and endoplasmic reticulum stress. 2013 Nov 1
71 23980364 [Curcumin combined FOLFOX induced cell apoptosis of gastric cancer and its mechanism research]. 2013 Jun 1
72 24079252 [Study on functions and mechanism of curcumin in inducing colorectal carcinoma cells LoVo apoptosis]. 2013 Jul 1
73 24083709 Curcumin inhibits human non-small cell lung cancer A549 cell proliferation through regulation of Bcl-2/Bax and cytochrome C. 2013 4
74 25206431 Curcumin ameliorates hippocampal neuron damage induced by human immunodeficiency virus-1. 2013 May 25 1
75 21711158 Curcumin induces small cell lung cancer NCI-H446 cell apoptosis via the reactive oxygen species-mediated mitochondrial pathway and not the cell death receptor pathway. 2012 Feb 1
76 22363450 Curcumin induces cell death in esophageal cancer cells through modulating Notch signaling. 2012 1
77 22469952 Synergistic anticancer activity of curcumin and bleomycin: an in vitro study using human malignant testicular germ cells. 2012 Jun 1
78 22502687 Antifibrotic effect of curcumin in TGF-β 1-induced myofibroblasts from human oral mucosa. 2012 1
79 22711176 Knockdown survivin expression reduces the efficacy of curcumin treatment in hepatocellular carcinoma cells. 2012 Oct 1
80 22886017 Curcumin-mediated neuroprotection against amyloid-β-induced mitochondrial dysfunction involves the inhibition of GSK-3β. 2012 1
81 21167259 Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis. 2011 Feb 11 1
82 21594647 Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosis. 2011 Nov 1
83 21616659 Curcumin improves MMC-based chemotherapy by simultaneously sensitising cancer cells to MMC and reducing MMC-associated side-effects. 2011 Sep 2
84 21617861 Apoptotic death in curcumin-treated NPC-TW 076 human nasopharyngeal carcinoma cells is mediated through the ROS, mitochondrial depolarization and caspase-3-dependent signaling responses. 2011 Aug 1
85 21729550 [Effect of curcumin in combination with bortezomib on proliferation and apoptosis of human multiple myeloma cell line H929 and its mechanism]. 2011 Jun 1
86 21857083 No protective effect of curcumin on hydrogen peroxide-induced cytotoxicity in HepG2 cells. 2011 1
87 22101335 Curcumin induces Apaf-1-dependent, p21-mediated caspase activation and apoptosis. 2011 Dec 1 6
88 22292626 Curcumin induces apoptosis involving bax/bcl-2 in human hepatoma SMMC-7721 cells. 2011 4
89 29147235 Curcumin Induces Apoptosis in EJ Bladder Cancer Cells via Modulating C-Myc and PI3K/Akt Signaling Pathway. 2011 Jun 1
90 19676105 Curcumin-induced apoptosis in ovarian carcinoma cells is p53-independent and involves p38 mitogen-activated protein kinase activation and downregulation of Bcl-2 and survivin expression and Akt signaling. 2010 Jan 1
91 20138829 Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells. 2010 Apr 9 1
92 20596601 The anti-cancer efficacy of curcumin scrutinized through core signaling pathways in glioblastoma. 2010 Aug 1
93 20600877 Curcumin p38-dependently enhances the anticancer activity of valproic acid in human leukemia cells. 2010 Oct 9 1
94 20605902 Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines. 2010 Oct 1
95 20651361 Curcumin induces apoptosis in human non-small cell lung cancer NCI-H460 cells through ER stress and caspase cascade- and mitochondria-dependent pathways. 2010 Jun 1
96 20661831 Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid, and silibinin on proliferation and apoptosis in acute myeloid leukemia cells. 2010 1
97 21036715 Curcumin-altered p53-response genes regulate radiosensitivity in p53-mutant Ewing's sarcoma cells. 2010 Oct 1
98 19191010 Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells. 2009 May 1
99 19235267 Curcumin induces apoptosis through the mitochondria-mediated apoptotic pathway in HT-29 cells. 2009 Feb 2
100 19288022 Curcumin inhibits proliferation and migration by increasing the Bax to Bcl-2 ratio and decreasing NF-kappaBp65 expression in breast cancer MDA-MB-231 cells. 2009 Apr 3