Melatonin

BCL2 associated X, apoptosis regulator ; Homo sapiens







67 Article(s)
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1 35365454 [Melatonin inhibits growth and metastasis of MDA-MB-231 breast cancer cells by activating autophagy]. 2022 Feb 20 6
2 35430637 Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway. 2022 Apr 17 1
3 33709108 Melatonin promotes male reproductive performance and increases testosterone synthesis in mammalian Leydig cells†. 2021 Jun 4 1
4 33859698 Melatonin Exerts Anti-Inflammatory, Antioxidant, and Neuromodulatory Effects That Could Potentially Be Useful in the Treatment of Vertigo. 2021 1
5 34087693 Molecular targets for the management of gastrointestinal cancer using melatonin, a natural endogenous body hormone. 2021 Aug 4
6 34580235 Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in gallbladder cancer cells. 2021 Sep 27 1
7 32012669 Effect of Melatonin on the In Vitro Maturation of Porcine Oocytes, Development of Parthenogenetically Activated Embryos, and Expression of Genes Related to the Oocyte Developmental Capability. 2020 Jan 27 1
8 32392192 [Melatonin Induces Apoptotic Cell Death in 3T3-L1 Preadipocytes]. 2020 Mar-Apr 2
9 32689938 Transcriptomic analysis on the effects of melatonin in gastrointestinal carcinomas. 2020 Jul 20 1
10 33352965 Melatonin Protects Cholangiocytes from Oxidative Stress-Induced Proapoptotic and Proinflammatory Stimuli via miR-132 and miR-34. 2020 Dec 18 1
11 33488926 Melatonin Protects Goat Spermatogonial Stem Cells against Oxidative Damage during Cryopreservation by Improving Antioxidant Capacity and Inhibiting Mitochondrial Apoptosis Pathway. 2020 1
12 31077716 Modulation of apoptosis by melatonin for improving cancer treatment efficiency: An updated review. 2019 Jul 1 1
13 31358006 Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis. 2019 Jul 29 1
14 31870319 Inhibition of autophagy triggers melatonin-induced apoptosis in glioblastoma cells. 2019 Dec 23 1
15 29207126 Melatonin enhances the apoptotic effects and modulates the changes in gene expression induced by docetaxel in MCF‑7 human breast cancer cells. 2018 Feb 1
16 29436019 Melatonin attenuates homocysteine-induced injury in human umbilical vein endothelial cells. 2018 Jun 1
17 29484412 Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway. 2018 Apr 1
18 29725496 Melatonin Inhibits Reactive Oxygen Species-Driven Proliferation, Epithelial-Mesenchymal Transition, and Vasculogenic Mimicry in Oral Cancer. 2018 1
19 30174783 Protective Effect of Melatonin against Oxidative Stress-Induced Apoptosis and Enhanced Autophagy in Human Retinal Pigment Epithelium Cells. 2018 1
20 30210141 Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage. 2018 Sep 13 1
21 27785753 Phytanic Acid-Induced Neurotoxicological Manifestations and Apoptosis Ameliorated by Mitochondria-Mediated Actions of Melatonin. 2017 Nov 1
22 28177678 Protective mechanisms of melatonin against hydrogen-peroxide-induced toxicity in human bone-marrow-derived mesenchymal stem cells. 2017 Jul 1
23 28246472 Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation. 2017 Feb 14 1
24 28415572 Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin. 2017 May 9 1
25 26607805 Melatonin enhances arsenic trioxide-induced cell death via sustained upregulation of Redd1 expression in breast cancer cells. 2016 Feb 15 1
26 27220903 Melatonin protects podocytes from angiotensin II-induced injury in an in vitro diabetic nephropathy model. 2016 Jul 2
27 27452798 Melatonin modulates glucocorticoid receptor mediated inhibition of antioxidant response and apoptosis in peripheral blood mononuclear cells. 2016 Nov 15 1
28 27465521 Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells. 2016 Oct 1
29 27477115 Melatonin modulates the functions of porcine granulosa cells via its membrane receptor MT2 in vitro. 2016 Sep 1
30 27484637 Melatonin-induced increase in sensitivity of human hepatocellular carcinoma cells to sorafenib is associated with reactive oxygen species production and mitophagy. 2016 Oct 1
31 27666165 Melatonin induces cell apoptosis in Mia PaCa-2 cells via the suppression of nuclear factor-κB and activation of ERK and JNK: A novel therapeutic implication for pancreatic cancer. 2016 Nov 1
32 25281200 Cytoprotective effect of melatonin against hypoxia/serum deprivation-induced cell death of bone marrow mesenchymal stem cells in vitro. 2015 Feb 5 1
33 25702644 Melatonin promotes Bax sequestration to mitochondria reducing cell susceptibility to apoptosis via the lipoxygenase metabolite 5-hydroxyeicosatetraenoic acid. 2015 Mar 4
34 25998836 Melatonin decreases cell proliferation, impairs myogenic differentiation and triggers apoptotic cell death in rhabdomyosarcoma cell lines. 2015 Jul 1
35 26176977 Melatonin attenuates the mitochondrial translocation of mitochondrial fission proteins and Bax, cytosolic calcium overload and cell death in methamphetamine-induced toxicity in neuroblastoma SH-SY5Y cells. 2015 Sep 2
36 26416428 Effects of normobaric oxygen and melatonin on reperfusion injury: role of cerebral microcirculation. 2015 Oct 13 1
37 26645893 Melatonin Induces Cell Apoptosis in AGS Cells Through the Activation of JNK and P38 MAPK and the Suppression of Nuclear Factor-Kappa B: a Novel Therapeutic Implication for Gastric Cancer. 2015 2
38 23975636 Protective effect of melatonin on methamphetamine-induced apoptosis in glioma cell line. 2014 Apr 1
39 24258787 Melatonin influences pancreatic cancerogenesis. 2014 Apr 1
40 24484372 Melatonin treatment induces interplay of apoptosis, autophagy, and senescence in human colorectal cancer cells. 2014 Apr 1
41 24799992 Melatonin attenuates cisplatin-induced HepG2 cell death via the regulation of mTOR and ERCC1 expressions. 2014 Apr 27 1
42 25000265 Overcoming hypoxic-resistance of tumor cells to TRAIL-induced apoptosis through melatonin. 2014 Jul 4 1
43 25219883 Melatonin as a proteasome inhibitor. Is there any clinical evidence? 2014 Oct 12 1
44 23245210 Melatonin is involved in the apoptosis and necrosis of pancreatic cancer cell line SW-1990 via modulating of Bcl-2/Bax balance. 2013 Mar 3
45 23488678 Melatonin mediates protective effects on inflammatory response induced by interleukin-1 beta in human mesenchymal stem cells. 2013 Aug 1
46 23824714 Protective effect of melatonin on bone marrow mesenchymal stem cells against hydrogen peroxide-induced apoptosis in vitro. 2013 Oct 1
47 21883444 Melatonin protects against rotenone-induced cell injury via inhibition of Omi and Bax-mediated autophagy in Hela cells. 2012 Jan 2
48 21889572 Melatonin: the smart killer: the human trophoblast as a model. 2012 Jan 2 1
49 21929682 Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro. 2012 Mar 1
50 22225575 Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. 2012 Apr 2