Biotin

pyruvate carboxylase ; Homo sapiens







54 Article(s)
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1 35063765 Differential growth inhibition, cell cycle arrest and apoptosis of MCF-7 and MDA-MB-231 cells to holocarboxylase synthetase suppression. 2022 Feb 19 1
2 33572391 Partial Biotinidase Deficiency Revealed Imbalances in Acylcarnitines Profile at Tandem Mass Spectrometry Newborn Screening. 2021 Feb 9 2
3 31697914 MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231 cells. 2019 Nov 30 2
4 30045381 Pyruvate Carboxylase Deficiency Type C: A Rare Cause of Acute Transient Flaccid Paralysis with Ketoacidosis. 2018 Dec 2
5 28271481 "Pyruvate Carboxylase, Structure and Function". 2017 1
6 28791550 Drug Delivery Nanoparticles with Locally Tunable Toxicity Made Entirely from a Light-Activatable Prodrug of Doxorubicin. 2017 Oct 1
7 28649521 Pyruvate carboxylase deficiency: An underestimated cause of lactic acidosis. 2015 Mar 2
8 22869039 Structure and function of biotin-dependent carboxylases. 2013 Mar 1
9 23698000 A substrate-induced biotin binding pocket in the carboxyltransferase domain of pyruvate carboxylase. 2013 Jul 5 3
10 24812517 Intake and urinary amounts of biotin in Japanese elementary school children, college students, and elderly persons. 2013 1
11 23098296 Localization of inhibitory antibodies to the biotin domain of human pyruvate carboxylase. 2012 Oct 1
12 21958016 Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli. 2011 Nov 15 1
13 20596761 A novel Doxorubicin prodrug with controllable photolysis activation for cancer chemotherapy. 2010 Sep 1
14 19306334 Structural insights on pathogenic effects of novel mutations causing pyruvate carboxylase deficiency. 2009 May 1
15 18297087 Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. 2008 Mar 1
16 18613815 Structure, mechanism and regulation of pyruvate carboxylase. 2008 Aug 1 2
17 17717183 Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme. 2007 Aug 24 1
18 10846444 [Importance of biotin metabolism]. 2000 Mar-Apr 1
19 10858297 Effects of Mg(2+) on the pre-steady-state kinetics of the biotin carboxylation reaction of pyruvate carboxylase. 2000 Jun 27 2
20 10229653 Structure, function and regulation of pyruvate carboxylase. 1999 May 15 2
21 9597748 Pyruvate carboxylase. 1998 Jan 1
22 9649849 The role of Mg2+ in biotin carboxylation in pyruvate carboxylase. 1998 May 1
23 9831077 Role of biotin-containing membranes and nuclear distribution in differentiating human endometrial cells. 1998 Dec 1 1
24 9056115 Lack of mutations in the biotin-binding region of the pyruvate carboxylase (PC) gene in a family with partial PC deficiency. 1997 Feb 2
25 8620009 Effects of acetyl CoA on the pre-steady-state kinetics of the biotin carboxylation reaction of pyruvate carboxylase. 1996 Mar 26 1
26 7822739 MRI, clinical, and biochemical features of partial pyruvate carboxylase deficiency. 1994 Oct 1
27 8251494 Locus of action of acetyl CoA in the biotin-carboxylation reaction of pyruvate carboxylase. 1993 Nov 30 1
28 8449348 The effects of pH on the binding of ATP and phosphate in the biotin carboxylation reaction of pyruvate carboxylase. 1993 Feb 1
29 2085665 Biotin for diabetic peripheral neuropathy. 1990 2
30 2679223 Pyruvate carboxylase as a model for oligosubstituted enzyme-ligand conjugates in homogeneous enzyme immunoassays. 1989 Oct 1 2
31 3101494 The French and North American phenotypes of pyruvate carboxylase deficiency, correlation with biotin containing protein by 3H-biotin incorporation, 35S-streptavidin labeling, and Northern blotting with a cloned cDNA probe. 1987 Jan 1
32 3555348 Sequence homology around the biotin-binding site of human propionyl-CoA carboxylase and pyruvate carboxylase. 1987 May 1 1
33 3814578 Decarboxylation of oxalacetate by pyruvate carboxylase. 1986 Dec 16 1
34 2868710 Distribution and degradation of biotin-containing carboxylases in human cell lines. 1985 Dec 1 1
35 3918814 Rapid differential diagnosis of carboxylase deficiencies and evaluation for biotin-responsiveness in a single blood sample. 1985 Jan 30 2
36 3939532 Pyruvate carboxylase deficiencies: complementation studies between "French" and "American" phenotypes in cultured fibroblasts. 1985 1
37 6548474 Molecular cloning of a cDNA for human pyruvate carboxylase. Structural relationship to other biotin-containing carboxylases and regulation of mRNA content in differentiating preadipocytes. 1984 Oct 25 4
38 6851181 The measurement of propionyl-CoA carboxylase and pyruvate carboxylase activity in hair roots: its use in the diagnosis of inherited biotin-dependent enzyme deficiencies. 1983 May 9 2
39 6803393 Lymphoblasts and diagnosis of pyruvate carboxylase deficiency. 1982 Jan 1
40 7104292 The determination of the availability to chicks of biotin in feed ingredients by a bioassay based on the response of blood pyruvate carboxylase (EC 6.4.1.1) activity. 1982 Jul 2
41 6112081 Deficient acetyl CoA carboxylase activity in multiple carboxylase deficiency. 1981 Apr 9 1
42 6794361 Biochemical characterization of biotin-responsive multiple carboxylase deficiency: heterogeneity within the bio genetic complementation group. 1981 Sep 1
43 7317813 Aspects of metabolism related to the occurrence of skin lesions in biotin-deficient chicks. 1981 Sep 1
44 7340821 Factors that influence the translocation of the N-carboxybiotin moiety between the two sub-sites of pyruvate carboxylase. 1981 Dec 1 2
45 6776949 Evidence for two genetic complementation groups in pyruvate carboxylase-deficient human fibroblast cell lines. 1980 Jun 3
46 35104 Biotin subunits of acetyl CoA carboxylase and pyruvate carboxylase from a thermophilic Bacillus. 1979 Feb 1
47 115903 Biotin-response organicaciduria. Multiple carboxylase defects and complementation studies with propionicacidemia in cultured fibroblasts. 1979 Dec 1
48 555586 Pyruvate carboxylase activities in red blood cells and liver of chicks and their dependency on biotin status. First results with activation assays.. 1979 3
49 562132 Pyruvate carboxylase: isolation of the biotin-containing tryptic peptide and the determination of its primary sequency. 1977 Sep 1
50 8990 Role of oxalacetate in lipoate effect on frog gastric mucosa. 1976 Jul 1