| 1 |
33170486 | Defining platelet response to acetylsalicylic acid: the relation between inhibition of serum thromboxane B2 and agonist-induced platelet aggregation. | 2021 Feb |
1 |
| 2 |
33796403 | Combination of EP4 antagonist MF-766 and anti-PD-1 promotes anti-tumor efficacy by modulating both lymphocytes and myeloid cells. | 2021 Mar 18 |
1 |
| 3 |
30710016 | Interactions of fatty acids, nonsteroidal anti-inflammatory drugs, and coxibs with the catalytic and allosteric subunits of cyclooxygenases-1 and -2. | 2019 Feb 1 |
1 |
| 4 |
30888847 | Effects of Aspirin on Growth Factor Release From Freshly Isolated Leukocyte-Rich Platelet-Rich Plasma in Healthy Men: A Prospective Fixed-Sequence Controlled Laboratory Study. | 2019 Apr |
2 |
| 5 |
30314310 | Cyclooxygenase-1 (COX-1) and COX-1 Inhibitors in Cancer: A Review of Oncology and Medicinal Chemistry Literature. | 2018 Oct 11 |
2 |
| 6 |
27629384 | Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants. | 2016 Nov |
2 |
| 7 |
27845343 | Directed transport of neutrophil-derived extracellular vesicles enables platelet-mediated innate immune response. | 2016 Nov 15 |
2 |
| 8 |
26672987 | Changes in PTGS1 and ALOX12 Gene Expression in Peripheral Blood Mononuclear Cells Are Associated with Changes in Arachidonic Acid, Oxylipins, and Oxylipin/Fatty Acid Ratios in Response to Omega-3 Fatty Acid Supplementation. | 2015 |
3 |
| 9 |
24207016 | Evaluation of laboratory methods routinely used to detect the effect of aspirin against new reference methods. | 2014 May |
1 |
| 10 |
23384979 | Mechanism of the irreversible inhibition of human cyclooxygenase-1 by aspirin as predicted by QM/MM calculations. | 2013 Mar |
1 |
| 11 |
23422285 | New direct and indirect methods for the detection of cyclooxygenase 1 acetylation by aspirin; the lack of aspirin resistance among healthy individuals. | 2013 Apr |
2 |
| 12 |
23473504 | Conformational effects on the pro-S hydrogen abstraction reaction in cyclooxygenase-1: an integrated QM/MM and MD study. | 2013 Mar 5 |
2 |
| 13 |
23830213 | TXA2 synthesis and COX1-independent platelet reactivity in aspirin-treated patients soon after acute cerebral stroke or transient ischaemic attack. | 2013 Aug |
1 |
| 14 |
23985963 | Thromboxane A(2) generation, in the absence of platelet COX-1 activity, in patients with and without atherothrombotic myocardial infarction. | 2013 |
1 |
| 15 |
24482730 | Rational Design of Novel Pyridinol-Fused Ring Acetaminophen Analogues. | 2013 Aug 8 |
1 |
| 16 |
21699540 | The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. | 2012 May |
1 |
| 17 |
22174077 | Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones. | 2012 Mar |
1 |
| 18 |
22481026 | Long-term CFTR inhibition modulates 15d-prostaglandin J2 in human pulmonary cells. | 2012 Jun |
1 |
| 19 |
22829846 | Rhinosinusitis and aspirin-exacerbated respiratory disease. | 2012 |
2 |
| 20 |
21127289 | Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis. | 2011 Feb |
2 |
| 21 |
21163909 | Human prostaglandin H synthase (hPHS)-1 and hPHS-2 in amphetamine analog bioactivation, DNA oxidation, and cytotoxicity. | 2011 Mar |
1 |
| 22 |
21403766 | Cyclooxygenase reaction mechanism of PGHS--evidence for a reversible transition between a pentadienyl radical and a new tyrosyl radical by nitric oxide trapping. | 2011 Mar |
2 |
| 23 |
21467029 | Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer. | 2011 May 27 |
1 |
| 24 |
20194532 | Asymmetric acetylation of the cyclooxygenase-2 homodimer by aspirin and its effects on the oxygenation of arachidonic, eicosapentaenoic, and docosahexaenoic acids. | 2010 Jun |
1 |
| 25 |
20227521 | Decrease in expression or activity of cytosolic phospholipase A2alpha increases cyclooxygenase-1 action: A cross-talk between key enzymes in arachidonic acid pathway in prostate cancer cells. | 2010 Jul |
1 |
| 26 |
20645164 | Expression of cyclooxygenase isoforms in the baculovirus expression system. | 2010 |
1 |
| 27 |
19028575 | Kinetic modelling of NSAID action on COX-1: focus on in vitro/in vivo aspects and drug combinations. | 2009 Jan 31 |
1 |
| 28 |
19210337 | Cyclooxygenase-2-derived prostaglandin E2 is involved in vascular endothelial growth factor production in interleukin-1alpha-stimulated human periodontal ligament cells. | 2009 Jun |
1 |
| 29 |
19218248 | Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers. | 2009 Apr 10 |
1 |
| 30 |
19433337 | Peroxide-induced radical formation at TYR385 and TYR504 in human PGHS-1. | 2009 Jun |
1 |
| 31 |
19928795 | Characterization of an AM404 analogue, N-(3-hydroxyphenyl)arachidonoylamide, as a substrate and inactivator of prostaglandin endoperoxide synthase. | 2009 Dec 29 |
4 |
| 32 |
19996015 | Association of cyclooxygenase-1-dependent and -independent platelet function assays with adverse clinical outcomes in aspirin-treated patients presenting for cardiac catheterization. | 2009 Dec 22 |
1 |
| 33 |
18435972 | Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease. | 2008 May 1 |
1 |
| 34 |
18536521 | COX-2 expression in oral lichen planus. | 2008 |
1 |
| 35 |
18670087 | Antiplatelet effect and selective binding to cyclooxygenase by molecular docking analysis of 3-alkylaminopropoxy-9,10-anthraquinone derivatives. | 2008 Aug |
1 |
| 36 |
18818754 | Role of linoleic Acid hydroperoxide preformed by cyclooxygenase-1 or -2 on the regulation of prostaglandin formation from arachidonic Acid by the respective enzyme. | 2008 Sep |
1 |
| 37 |
17191216 | Novel cyclooxygenase-catalyzed bioactive prostaglandin F2alpha from physiology to new principles in inflammation. | 2007 Jul |
1 |
| 38 |
17209563 | Oxyferryl heme and not tyrosyl radical is the likely culprit in prostaglandin H synthase-1 peroxidase inactivation. | 2007 Jan 16 |
2 |
| 39 |
17242290 | Letter by Kronish et al regarding article, "Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance". | 2007 Jan 23 |
1 |
| 40 |
17301694 | Identification and functional characterization of polymorphisms in human cyclooxygenase-1 (PTGS1). | 2007 Feb |
6 |
| 41 |
16551714 | Sex differences in platelet reactivity and response to low-dose aspirin therapy. | 2006 Mar 22 |
1 |
| 42 |
16606823 | Partnering between monomers of cyclooxygenase-2 homodimers. | 2006 Apr 18 |
1 |
| 43 |
16785341 | Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance. | 2006 Jun 27 |
2 |
| 44 |
16952710 | Prostacyclin production in tryptase and thrombin stimulated human bladder endothelial cells: effect of pretreatment with phospholipase A2 and cyclooxygenase inhibitors. | 2006 Oct |
1 |
| 45 |
15869467 | Oxygenation by COX-2 (cyclo-oxygenase-2) of 3-HETE (3-hydroxyeicosatetraenoic acid), a fungal mimetic of arachidonic acid, produces a cascade of novel bioactive 3-hydroxyeicosanoids. | 2005 Sep 15 |
1 |
| 46 |
15921208 | New immunohistologic findings on the differential role of cyclooxygenase 1 and cyclooxygenase 2 in nasal polyposis. | 2005 Mar-Apr |
2 |
| 47 |
16433444 | [New pathophysiological concepts on aspirin hypersensitivity (Widal syndrome); diagnostic and therapeutic consequences]. | 2005 Jun |
1 |
| 48 |
15084746 | Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells. | 2004 Apr 27 |
1 |
| 49 |
12545150 | Genetic variation in cyclooxygenase 1: effects on response to aspirin. | 2003 Jan |
2 |
| 50 |
12637362 | 17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation. | 2003 Jul |
1 |