Sphingomyelins

sphingomyelin phosphodiesterase 1, acid lysosomal ; Mus musculus







42 Article(s)
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1 33897374 Tonic Control of Secretory Acid Sphingomyelinase Over Ventral Hippocampal Synaptic Transmission and Neuron Excitability. 2021 1
2 31883406 Acid sphingomyelinase deficiency exacerbates LPS-induced experimental periodontitis. 2020 Apr 1
3 32481596 Mitochondrial Ceramide Effects on the Retinal Pigment Epithelium in Diabetes. 2020 May 28 1
4 33057972 Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia. 2020 Oct 14 2
5 30556232 Immunoregulatory role of acid sphingomyelinase in allergic asthma. 2019 Apr 1
6 31214184 T Cell-Specific Overexpression of Acid Sphingomyelinase Results in Elevated T Cell Activation and Reduced Parasitemia During Plasmodium yoelii Infection. 2019 1
7 31275322 Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis. 2019 1
8 31636468 Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin. 2019 Dec 1
9 31766565 In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism. 2019 Nov 21 1
10 28842833 Ceramide and Its Related Neurochemical Networks as Targets for Some Brain Disorder Therapies. 2018 Feb 1
11 29908119 CD4+ Foxp3+ regulatory T cell-mediated immunomodulation by anti-depressants inhibiting acid sphingomyelinase. 2018 Sep 25 1
12 27620840 Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease. 2017 May 1
13 28462076 Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis. 2017 May 1
14 26792860 Structural Basis for Nucleotide Hydrolysis by the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3A. 2016 Mar 18 1
15 27512981 Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development. 2016 1
16 27571014 Suppression of Acid Sphingomyelinase Protects the Retina from Ischemic Injury. 2016 Aug 1 1
17 25251606 Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS. 2015 Jan 3
18 26129774 Acid sphingomyelinase (aSMase) deficiency leads to abnormal microglia behavior and disturbed retinal function. 2015 Aug 21 1
19 26168297 Lack of Acid Sphingomyelinase Induces Age-Related Retinal Degeneration. 2015 1
20 26253821 Regulation of ceramide generation during macrophage apoptosis by ASMase and de novo synthesis. 2015 Nov 1
21 24164338 Role of acid sphingomyelinase in the regulation of mast cell function. 2014 Jan 2
22 23108456 TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice. 2013 Jan 2
23 23563650 Using ASMase knockout mice to model human diseases. 2013 1
24 22328778 Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium. 2012 May 1
25 21674735 Adeno-associated virus-mediated expression of acid sphingomyelinase decreases atherosclerotic lesion formation in apolipoprotein E(-/-) mice. 2011 Jun 2
26 21063112 Acid sphingomyelinase deficiency attenuates bleomycin-induced lung inflammation and fibrosis in mice. 2010 1
27 19231265 Pulmonary delivery of recombinant acid sphingomyelinase improves clearance of lysosomal sphingomyelin from the lungs of a murine model of Niemann-Pick disease. 2009 May 1
28 19390577 Synaptic vesicle docking: sphingosine regulates syntaxin1 interaction with Munc18. 2009 1
29 18032586 Anomalous surface distribution of glycosyl phosphatidyl inositol-anchored proteins in neurons lacking acid sphingomyelinase. 2008 Feb 1
30 18376404 Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis. 2008 Apr 1
31 17686472 Intraparenchymal injections of acid sphingomyelinase results in regional correction of lysosomal storage pathology in the Niemann-Pick A mouse. 2007 Oct 1
32 15371271 Effects of acid sphingomyelinase deficiency on male germ cell development and programmed cell death. 2005 Jan 1
33 15702401 Preimplantation diagnosis of a lysosomal storage disorder by in situ enzymatic activity: 'proof of principle' in acid sphingomyelinase-deficient mice. 2005 1
34 15564580 Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology. 2004 Nov 24 1
35 15669680 Elevation of lung surfactant phosphatidylcholine in mouse models of Sandhoff and of Niemann-Pick A disease. 2004 1
36 12495943 Alveolar lipoproteinosis in an acid sphingomyelinase-deficient mouse model of Niemann-Pick disease. 2003 Mar 2
37 11096096 Natural ceramide reverses Fas resistance of acid sphingomyelinase(-/-) hepatocytes. 2001 Mar 16 1
38 10800075 Perturbation of membrane microdomains reduces mitogenic signaling and increases susceptibility to apoptosis after T cell receptor stimulation. 2000 May 1
39 11220788 Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis. 2000 Oct 1
40 9864149 Fluorescence-based selection of gene-corrected hematopoietic stem and progenitor cells from acid sphingomyelinase-deficient mice: implications for Niemann-Pick disease gene therapy and the development of improved stem cell gene transfer procedures. 1999 Jan 1 1
41 10606630 Roles for tumor necrosis factor receptor p55 and sphingomyelinase in repairing the cutaneous permeability barrier. 1999 Dec 1
42 9770326 Acid sphingomyelinase-derived ceramide is not required for inflammatory cytokine signalling in murine macrophages. 1998 Sep 2