Proline

aldehyde dehydrogenase 18 family member A1 ; Homo sapiens







31 Article(s)
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1 35286254 Structural basis of dynamic P5CS filaments. 2022 Mar 14 2
2 35453378 Physiological, Biochemical and Molecular Response of Different Winter Wheat Varieties under Drought Stress at Germination and Seedling Growth Stage. 2022 Mar 31 1
3 32770108 Pyrroline-5-carboxylate synthase senses cellular stress and modulates metabolism by regulating mitochondrial respiration. 2021 Jan 2
4 32798076 Tremor as an early sign of hereditary spastic paraplegia due to mutations in ALDH18A1. 2021 Jan 3
5 33465163 Association of high-risk neuroblastoma classification based on expression profiles with differentiation and metabolism. 2021 2
6 33646427 Reprogramming of mitochondrial proline metabolism promotes liver tumorigenesis. 2021 Dec 4
7 34390414 Proline metabolism in cancer. 2021 Dec 3
8 32516727 Melatonin and calcium function synergistically to promote the resilience through ROS metabolism under arsenic-induced stress. 2020 Nov 5 1
9 32637352 Salubrinal in Combination With 4E1RCat Synergistically Impairs Melanoma Development by Disrupting the Protein Synthetic Machinery. 2020 3
10 32960509 Proteomic patterns associated with response to breast cancer neoadjuvant treatment. 2020 Sep 1
11 30853934 Hereditary Spastic Paraplegia Is a Common Phenotypic Finding in ARG1 Deficiency, P5CS Deficiency and HHH Syndrome: Three Inborn Errors of Metabolism Caused by Alteration of an Interconnected Pathway of Glutamate and Urea Cycle Metabolism. 2019 1
12 30973753 Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts. 2019 Nov 2
13 29084919 Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma. 2018 Jan 15 1
14 28510193 Characterization of LhSorP5CS, a gene catalyzing proline synthesis in Oriental hybrid lily Sorbonne: molecular modelling and expression analysis. 2017 Dec 4
15 26829900 ALDH18A1-related cutis laxa syndrome with cyclic vomiting. 2016 Aug 2
16 26026163 Alteration of ornithine metabolism leads to dominant and recessive hereditary spastic paraplegia. 2015 Aug 4
17 26082174 Disruption of Proline Synthesis in Melanoma Inhibits Protein Production Mediated by the GCN2 Pathway. 2015 Oct 4
18 26320891 Recurrent De Novo Mutations Affecting Residue Arg138 of Pyrroline-5-Carboxylate Synthase Cause a Progeroid Form of Autosomal-Dominant Cutis Laxa. 2015 Sep 3 4
19 23041351 The nitric oxide donor sodium nitroprusside regulates polyamine and proline metabolism in leaves of Medicago truncatula plants. 2013 Mar 2
20 24068435 Molecular evolution of plant P5CS gene involved in proline biosynthesis. 2013 Nov 5
21 22170564 Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine. 2012 Sep 3
22 20387057 A new method for accurately measuring Delta(1)-pyrroline-5-carboxylate synthetase activity. 2010 1
23 18036351 Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress. 2008 Feb 15 3
24 18401542 Human Delta1-pyrroline-5-carboxylate synthase: function and regulation. 2008 Nov 2
25 18478038 A missense mutation in ALDH18A1, encoding Delta1-pyrroline-5-carboxylate synthase (P5CS), causes an autosomal recessive neurocutaneous syndrome. 2008 Oct 1
26 15517380 Delta1-pyrroline-5-carboxylate synthase deficiency: neurodegeneration, cataracts and connective tissue manifestations combined with hyperammonaemia and reduced ornithine, citrulline, arginine and proline. 2005 Jan 2
27 11092761 Hyperammonemia with reduced ornithine, citrulline, arginine and proline: a new inborn error caused by a mutation in the gene encoding delta(1)-pyrroline-5-carboxylate synthase. 2000 Nov 22 3
28 10037775 Molecular enzymology of mammalian Delta1-pyrroline-5-carboxylate synthase. Alternative splice donor utilization generates isoforms with different sensitivity to ornithine inhibition. 1999 Mar 5 3
29 9622938 [A new inherited metabolic disease: delta1-pyrroline 5-carboxylate synthetase deficiency]. 1998 1
30 8761662 Database cloning human delta 1-pyrroline-5-carboxylate synthetase (P5CS) cDNA: a bifunctional enzyme catalyzing the first 2 steps in proline biosynthesis. 1996 Mar 5
31 6115302 Regulation of proline biosynthesis: the inhibition of pyrroline-5-carboxylate synthase activity by ornithine. 1981 Sep 1