2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase kinase 1 ; Homo sapiens







451 Article(s)
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51 22441978 Acetylcholine induces mesenchymal stem cell migration via Ca2+ /PKC/ERK1/2 signal pathway. 2012 Aug 1
52 22445893 Thyroglobulin (Tg) activates MAPK pathway to induce thyroid cell growth in the absence of TSH, insulin and serum. 2012 Apr 13 1
53 22479527 EGF-induced EMT and invasiveness in serous borderline ovarian tumor cells: a possible step in the transition to low-grade serous carcinoma cells? 2012 1
54 22543706 E-cadherin promotes proliferation of human ovarian cancer cells in vitro via activating MEK/ERK pathway. 2012 Jun 1
55 22747445 Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion. 2012 Oct 1 1
56 22867530 Cell death triggered by synthetic flavonoids in human leukemia cells is amplified by the inhibition of extracellular signal-regulated kinase signaling. 2012 Sep 2
57 23018815 ERK is involved in tooth-pressure-induced Fos expression in Vc neurons. 2012 Dec 1
58 23149874 Nicotine induces the expression of C-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2012 Nov 1
59 23190603 Cordyceps militaris and mycelial fermentation induced apoptosis and autophagy of human glioblastoma cells. 2012 Nov 29 2
60 20451919 Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways. 2011 Aug 1
61 21074412 MAPK and PI3K signalling differentially regulate angiogenic and lymphangiogenic cytokine secretion in squamous cell carcinoma of the head and neck. 2011 Mar 1
62 21109980 Esculetin inhibits cell proliferation through the Ras/ERK1/2 pathway in human colon cancer cells. 2011 Jan 1
63 21138763 The combi-targeting concept: mechanism of action of the pleiotropic combi-molecule RB24 and discovery of a novel cell signaling-based combination principle. 2011 Apr 1
64 21236341 Estrogenic effect of the MEK1 inhibitor PD98059 on endogenous estrogen receptor alpha and beta. 2011 Mar 3
65 21297032 Molecular regulation of NADPH oxidase 5 via the MAPK pathway. 2011 Apr 1
66 21325823 Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages. 2011 2
67 21520151 VEGF-A-induced immature DCs not mature DCs differentiation into endothelial-like cells through ERK1/2-dependent pathway. 2011 Jun 1
68 21554891 Loss of p120 catenin upregulates transcription of pro-inflammatory adhesion molecules in human endothelial cells. 2011 Sep 1
69 21575204 AGE-BSA down-regulates endothelial connexin43 gap junctions. 2011 May 16 1
70 21684323 The KDEL receptor induces autophagy to promote the clearance of neurodegenerative disease-related proteins. 2011 Sep 8 2
71 21705076 The stimulation of osteogenic differentiation of human adipose-derived stem cells by ionic products from akermanite dissolution via activation of the ERK pathway. 2011 Oct 1
72 21711521 Elevated transforming growth factor β and mitogen-activated protein kinase pathways mediate fibrotic traits of Dupuytren's disease fibroblasts. 2011 Jun 28 1
73 21784060 The NADPH oxidase cytosolic component p67phox is constitutively phosphorylated in human neutrophils: Regulation by a protein tyrosine kinase, MEK1/2 and phosphatases 1/2A. 2011 Nov 1 1
74 21901168 Identification of an In Vivo MEK/WOX1 Complex as a Master Switch for Apoptosis in T Cell Leukemia. 2011 May 2
75 19903460 Fibroblast growth factor-2 induces osteogenic differentiation through a Runx2 activation in vascular smooth muscle cells. 2010 Apr 2 1
76 20118622 Extracellular signal-regulated kinase (ERK) inhibition attenuates cigarette smoke extract (CSE) induced-death inducing signaling complex (DISC) formation in human lung fibroblasts (MRC-5) cells. 2010 Feb 2
77 20179161 The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1. 2010 Mar 1
78 20200209 Transient hypoxia induces ERK-dependent anti-apoptotic cell survival in endothelial cells. 2010 Jun 1
79 20466409 Mechanism of collagen-induced release of 5-HT, PDGF-AB and sCD40L from human platelets: role of HSP27 phosphorylation via p44/p42 MAPK. 2010 Jul 1
80 20479004 The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer. 2010 Jul 30 1
81 20702723 The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor. 2010 Dec 1
82 20725992 Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas. 2010 Nov 1
83 20878765 The constitutive production of the endocannabinoid 2-arachidonoylglycerol participates in oligodendrocyte differentiation. 2010 Dec 1
84 19103756 Plk3 interacts with and specifically phosphorylates VRK1 in Ser342, a downstream target in a pathway that induces Golgi fragmentation. 2009 Mar 1
85 19254730 Fluvastatin attenuates IGF-1-induced ERK1/2 activation and cell proliferation by mevalonic acid depletion in human mesangial cells. 2009 May 22 2
86 19307750 Calcitonin induces connective tissue growth factor through ERK1/2 signaling in renal tubular cells. 2009 May 31 1
87 19319572 Evidence for the involvement of endothelial cell products in adrenal CITED2 expression. 2009 May 1
88 19339632 Aldosterone-induced mesangial cell proliferation is mediated by EGF receptor transactivation. 2009 Jun 1
89 19405034 RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways. 2009 May 1
90 19426837 The green tea polyphenol (-)-epigallocatechin-3-gallate inhibits leukocyte activation by bacterial formylpeptide through the receptor FPR. 2009 Aug 1
91 19507016 Tec kinase mediating IL-8 transcription in monocytes stimulated with LPS. 2009 Aug 1
92 19509115 K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signaling pathways. 2009 Jun 1
93 19568240 Characterisation of fibronectin-mediated FAK signalling pathways in lung cancer cell migration and invasion. 2009 Jul 21 1
94 19581418 Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1. 2009 Oct 1
95 19701583 [Dual effects of different concentrations of alpha-synuclein on the neurotoxicity of 6-hydroxydopamine in SH-SY5Y cells]. 2009 Aug 25 1
96 19815548 Calnexin phosphorylation attenuates the release of partially misfolded alpha1-antitrypsin to the secretory pathway. 2009 Dec 11 1
97 19833733 Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway. 2009 Nov 27 1
98 19892399 Hypoxia enhances FGF2- and VEGF-stimulated human placental artery endothelial cell proliferation: roles of MEK1/2/ERK1/2 and PI3K/AKT1 pathways. 2009 Dec 1
99 17911534 FP prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a Ras/Raf/mitogen-activated protein kinase signaling cascade. 2008 Jan 2
100 17995938 PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases. 2008 Jan 1