2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase kinase 7 ; Homo sapiens







761 Article(s)
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1 34951997 ERK-mediated upregulation of matrix metalloproteinase-2 promotes the invasiveness in human oral squamous cell carcinoma (OSCC). 2022 Feb 1 2
2 35078573 [Valproate up-regulates the expression of NKG2DL through the MEK/ERK signaling pathway to enhance the killing effect of NK cells on A375 human melanoma cells]. 2022 Jan 1
3 35237605 Role of Integrin αvβ3 in Doxycycline-Induced Anti-Proliferation in Breast Cancer Cells. 2022 1
4 35301650 Exogenous interleukin-1 beta promotes the proliferation and migration of HeLa cells via the MEK/ERK signaling pathway. 2022 May 2
5 35401684 Mxi1-0 Promotes Hypoxic Pulmonary Hypertension Via ERK/c-Myc-dependent Proliferation of Arterial Smooth Muscle Cells. 2022 1
6 35447220 Molecular and cellular outcomes of quercetin actions on healthy and tumor osteoblasts. 2022 Aug 1
7 33035625 Anti-inflammatory effect of IGF-1 is mediated by IGF-1R cross talk with GPER in MPTP/MPP+-induced astrocyte activation. 2021 Jan 1 1
8 33249095 MAPK pathway and SIRT1 are involved in the down-regulation of secreted osteopontin expression by genistein in metastatic cancer cells. 2021 Jan 15 1
9 33290316 A PI3K inhibitor-induced growth inhibition of cancer cells is linked to MEK-ERK pathway. 2021 Jun 1 2
10 33552829 MiR-192-5p regulates the proliferation and apoptosis of cholangiocarcinoma cells by activating MEK/ERK pathway. 2021 Feb 2
11 33784561 BarH-like homeobox 1 induces the progression of cell malignant phenotype in endometrial carcinoma through the regulation of ERK/MEK signaling pathway. 2021 Jun 2
12 33946902 Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells. 2021 Apr 29 1
13 34051057 Activation of the mitogen-activated protein kinase ERK1/2 signaling pathway suppresses the expression of ChREBPα and β in HepG2 cells. 2021 Jul 1
14 34066541 Activated ERK Signaling Is One of the Major Hub Signals Related to the Acquisition of Radiotherapy-Resistant MDA-MB-231 Breast Cancer Cells. 2021 May 6 2
15 34354953 DNA Polymerase Iota Promotes Esophageal Squamous Cell Carcinoma Proliferation Through Erk-OGT-Induced G6PD Overactivation. 2021 1
16 34475057 HGF-mediated Up-regulation of PHLDA2 Is Associated With Apoptosis in Gastric Cancer. 2021 Sep 1
17 31900222 Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways. 2020 Jan 3 1
18 31959867 TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency. 2020 Jan 1
19 32065117 Huai Qi Huang Potentiates Dexamethasone-Mediated Lethality in Acute Lymphoblastic Leukemia Cells by Upregulating Glucocorticoid Receptor α. 2020 Feb 17 1
20 32468028 The TLR4/ERK/PD‑L1 axis may contribute to NSCLC initiation. 2020 Aug 1
21 32572729 Vimentin plays an important role in the promotion of breast cancer cell migration and invasion by leucine aminopeptidase 3. 2020 Oct 1
22 32582994 Downregulation of microRNA‑143 promotes osteogenic differentiation of human adipose‑derived mesenchymal stem cells through the k‑Ras/MEK/ERK signaling pathway. 2020 Sep 2
23 32721671 Lithium promotes malignant transformation of nontumorigenic cells in vitro. 2020 Nov 20 1
24 32774719 Overexpression of TEM8 promotes ovarian cancer progression via Rac1/Cdc42/JNK and MEK/ERK/STAT3 signaling pathways. 2020 1
25 32774743 Extracorporeal cardiac shock waves therapy promotes function of endothelial progenitor cells through PI3K/AKT and MEK/ERK signaling pathways. 2020 1
26 32964977 Downregulation of lncRNA CCHE1 inhibits cell proliferation, migration and invasion by suppressing MEK/ERK/c-MYC pathway in nasopharyngeal carcinoma. 2020 Sep 1
27 33911740 Ultraviolet B Downregulated Aquaporin 1 Expression via the MEK/ERK pathway in the Dermal Fibroblasts. 2020 Jun 1
28 30340049 Role of eIF3a in 4-amino-2-trifluoromethyl-phenyl retinate-induced cell differentiation in human chronic myeloid leukemia K562 cells. 2019 Jan 30 1
29 30641047 A physiological concentration of luteolin induces phase II drug-metabolizing enzymes through the ERK1/2 signaling pathway in HepG2 cells. 2019 Mar 15 1
30 30689107 Density-dependent ERK MAPK expression regulates MMP-9 and influences growth. 2019 Jun 1
31 30839135 TNF-α mediated MEK-ERK signaling in invasion with putative network involving NF-κB and STAT-6: a new perspective in glioma. 2019 Nov 1
32 31269957 Cathepsin L-induced galectin-1 may act as a proangiogenic factor in the metastasis of high-grade serous carcinoma. 2019 Jul 3 1
33 31608140 Dual-Targeting AKT2 and ERK in cancer stem-like cells in neuroblastoma. 2019 Sep 24 1
34 31799197 FAM53A Affects Breast Cancer Cell Proliferation, Migration, and Invasion in a p53-Dependent Manner. 2019 2
35 31975773 Role of MEK-ERK signaling mediated adhesion of glioma cells to extra-cellular matrix: Possible implication on migration and proliferation. 2019 Apr 2
36 29108991 SETDB1-mediated FosB regulation via ERK2 is associated with an increase in cell invasiveness during anticancer drug treatment of A549 human lung cancer cells. 2018 Jan 1 1
37 29154827 Secretogranin III promotes angiogenesis through MEK/ERK signaling pathway. 2018 Jan 1 1
38 29360846 The activation of G protein-coupled estrogen receptor induces relaxation via cAMP as well as potentiates contraction via EGFR transactivation in porcine coronary arteries. 2018 1
39 29380233 p38 differentially regulates ERK, p21, and mitogenic signalling in two pancreatic carcinoma cell lines. 2018 Dec 1
40 29405768 Diepoxybutane-induced apoptosis is mediated through the ERK1/2 pathway. 2018 Oct 1
41 29422996 Melatonin regulates CRE-dependent gene transcription underlying osteoblast proliferation by activating Src and PKA in parallel. 2018 2
42 29546069 Involvement of P2X7 Receptor in Proliferation and Migration of Human Glioma Cells. 2018 1
43 29656183 Hispidulin inhibits hepatocellular carcinoma growth and metastasis through AMPK and ERK signaling mediated activation of PPARγ. 2018 Jul 1
44 29763915 Serum from Chronic Hepatitis B Patients Promotes Growth and Proliferation via the IGF-II/IGF-IR/MEK/ERK Signaling Pathway in Hepatocellular Carcinoma Cells. 2018 1
45 30229281 [Regulator proteins of actin dynamics as possible targets of antineoplastic therapies]. 2018 Dec 1
46 30337961 Synergistic inhibition of MEK/ERK and BRAF V600E with PD98059 and PLX4032 induces sodium/iodide symporter (NIS) expression and radioiodine uptake in BRAF mutated papillary thyroid cancer cells. 2018 1
47 30465574 Licochalcone A inhibits the invasive potential of human glioma cells by targeting the MEK/ERK and ADAM9 signaling pathways. 2018 Dec 13 1
48 30466991 Berberine down-regulates IL-8 expression through inhibition of the EGFR/MEK/ERK pathway in triple-negative breast cancer cells. 2018 Nov 15 1
49 27021766 Citrus peel polymethoxyflavones nobiletin and tangeretin suppress LPS- and IgE-mediated activation of human intestinal mast cells. 2017 Jun 1
50 27400655 H4R activation utilizes distinct signaling pathways for the production of RANTES and IL-13 in human mast cells. 2017 Apr 1