Title : MAPK pathway and SIRT1 are involved in the down-regulation of secreted osteopontin expression by genistein in metastatic cancer cells.

Pub. Date : 2021 Jan 15

PMID : 33249095






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Knockdown of ERK1/2 and PD98059, the inhibitor of MEK, promoted secreted OPN expression in vitro in these cells; while, the transfection of the constitutive active ERK2 (L73P and S151D) decreased the secreted OPN expression. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase kinase 7 Homo sapiens