Glucose

NLR family pyrin domain containing 3 ; Homo sapiens







65 Article(s)
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1 34997266 Pyrroloquinoline quinone ameliorates diabetic cardiomyopathy by inhibiting the pyroptosis signaling pathway in C57BL/6 mice and AC16 cells. 2022 Jun 1
2 35182568 Epac1 and PKA regulate of P2X7 and NLRP3 inflammasome proteins in the retinal vasculature. 2022 May 1
3 35584771 Agonism of GPR120 Prevented High Glucose-Induced Apoptosis of Retinal Endothelial Cells through Inhibiting NLRP3 Inflammasome. 2022 May 18 1
4 33404978 Telmisartan Inhibits the NLRP3 Inflammasome by Activating the PI3K Pathway in Neural Stem Cells Injured by Oxygen-Glucose Deprivation. 2021 Apr 1
5 33546399 NLRP3 Inflammasome at the Interface of Inflammation, Endothelial Dysfunction, and Type 2 Diabetes. 2021 Feb 3 1
6 33729569 Protective mechanisms of Taiwanese green propolis toward high glucose-induced inflammation via NLRP3 inflammasome signaling pathway in human gingival fibroblasts. 2021 Aug 3
7 33806797 NLRP3 Inflammasome: Potential Role in Obesity Related Low-Grade Inflammation and Insulin Resistance in Skeletal Muscle. 2021 Mar 23 1
8 34058229 VDAC1 regulates mitophagy in NLRP3 inflammasome activation in retinal capillary endothelial cells under high-glucose conditions. 2021 Aug 1
9 34084773 Enhanced mPGES-1 Contributes to PD-Related Peritoneal Fibrosis via Activation of the NLRP3 Inflammasome. 2021 1
10 34145545 Targeting NLRP3 inflammasome as a chief instigator of obesity, contributing to local adipose tissue inflammation and insulin resistance. 2021 Aug 1
11 34198548 Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma. 2021 Jun 14 1
12 34338149 Omarigliptin ameliorated high glucose-induced nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome activation through activating adenosine monophosphate-activated protein kinase α (AMPKα) in renal glomerular endothelial cells. 2021 Dec 1
13 34576117 Acute Glucose Shift Induces the Activation of the NLRP3 Inflammasome in THP-1 Cells. 2021 Sep 15 5
14 34831052 NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions. 2021 Oct 21 1
15 31703838 NLRP3 inflammasome negatively regulates podocyte autophagy in diabetic nephropathy. 2020 Jan 15 3
16 31705795 Allopurinol inhibits excess glucose-induced trophoblast IL-1β and ROS production. 2020 Jan 1
17 31885713 Hydrogen sulfide modulates high glucose-induced NLRP3 inflammasome activation in 3T3-L1 adipocytes. 2020 Jan 2
18 31938471 The antagonism of 6-shogaol in high-glucose-activated NLRP3 inflammasome and consequent calcification of human artery smooth muscle cells. 2020 2
19 32018221 MiR-130a alleviated high-glucose induced retinal pigment epithelium (RPE) death by modulating TNF-α/SOD1/ROS cascade mediated pyroptosis. 2020 May 2
20 32062019 The Molecular Mechanisms of Excessive Hippocampal Endoplasmic Reticulum Stress Depressing Cognition-related Proteins Expression and the Regulatory Effects of Nrf2. 2020 Apr 1 1
21 32298723 The impact of hyperglycaemia on PKM2-mediated NLRP3 inflammasome/stress granule signalling in macrophages and its correlation with plaque vulnerability: an in vivo and in vitro study. 2020 Jun 2
22 32329444 HDAC6 inhibitor Cay10603 inhibits high glucose-induced oxidative stress, inflammation and apoptosis in retinal pigment epithelial cells via regulating NF-κB and NLRP3 inflammasome pathway. 2020 Mar 1
23 32391974 LncRNA MALAT1 promoted high glucose-induced pyroptosis of renal tubular epithelial cell by sponging miR-30c targeting for NLRP3. 2020 Sep 1
24 32420343 High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis. 2020 2
25 32439949 High glucose mediates NLRP3 inflammasome activation via upregulation of ELF3 expression. 2020 May 21 3
26 32650532 The NLRP3 Inflammasome Role in the Pathogenesis of Pregnancy Induced Hypertension and Preeclampsia. 2020 Jul 8 1
27 32707731 Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition. 2020 Jul 19 1
28 33064063 The Warburg effect promoted the activation of the NLRP3 inflammasome induced by Ni-refining fumes in BEAS-2B cells. 2020 Aug 1
29 30471618 The effect of high glucose-based peritoneal dialysis fluids on thioredoxin-interacting protein expression in human peritoneal mesothelial cells. 2019 Jan 5
30 30591217 Long noncoding RNA MALAT1 promotes high glucose-induced human endothelial cells pyroptosis by affecting NLRP3 expression through competitively binding miR-22. 2019 Feb 5 2
31 30660990 Anagliptin ameliorates high glucose- induced endothelial dysfunction via suppression of NLRP3 inflammasome activation mediated by SIRT1. 2019 Mar 2
32 30804327 The classical NLRP3 inflammasome controls FADD unconventional secretion through microvesicle shedding. 2019 Feb 25 1
33 30906223 Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR. 2019 5
34 31108165 Downregulation of hsa_circ_0068087 ameliorates TLR4/NF-κB/NLRP3 inflammasome-mediated inflammation and endothelial cell dysfunction in high glucose conditioned by sponging miR-197. 2019 Aug 15 1
35 31178664 Hydrogen Sulfide Attenuates High Glucose-Induced Human Retinal Pigment Epithelial Cell Inflammation by Inhibiting ROS Formation and NLRP3 Inflammasome Activation. 2019 1
36 31302140 Dulaglutide inhibits high glucose- induced endothelial dysfunction and NLRP3 inflammasome activation. 2019 Aug 15 4
37 31351069 The protective effects of orexin a against high glucose-induced activation of NLRP3 inflammasome in human vascular endothelial cells. 2019 Sep 15 3
38 31354329 Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells. 2019 1
39 31571967 NLRP3 inflammasome promotes diabetes-induced endothelial inflammation and atherosclerosis. 2019 3
40 31638409 Resveratrol inhibits high-glucose-induced inflammatory "metabolic memory" in human retinal vascular endothelial cells through SIRT1-dependent signaling. 2019 Dec 1
41 31736762 Rapamycin Attenuates High Glucose-Induced Inflammation Through Modulation of mTOR/NF-κB Pathways in Macrophages. 2019 2
42 29682582 Vitamin D3 Protects against Diabetic Retinopathy by Inhibiting High-Glucose-Induced Activation of the ROS/TXNIP/NLRP3 Inflammasome Pathway. 2018 1
43 30119194 The protective effect of formononetin on cognitive impairment in streptozotocin (STZ)-induced diabetic mice. 2018 Oct 1
44 30307163 Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells 2018 Oct 1 2
45 28164132 NLRP3 Inflammasome Expression and Signaling in Human Diabetic Wounds and in High Glucose Induced Macrophages. 2017 5
46 28726778 Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction. 2017 Jul 20 3
47 28798291 Function of NLRP3 in the Pathogenesis and Development of Diabetic Nephropathy. 2017 Aug 11 1
48 28849014 Zinc inhibits high glucose-induced NLRP3 inflammasome activation in human peritoneal mesothelial cells. 2017 Oct 1
49 28854426 Autophagy Inhibition Contributes to ROS-Producing NLRP3-Dependent Inflammasome Activation and Cytokine Secretion in High Glucose-Induced Macrophages. 2017 7
50 28972154 Neutrophil microparticle production and inflammasome activation by hyperglycemia due to cytoskeletal instability. 2017 Nov 3 1