Pub. Date : 2019 Aug 15
PMID : 31302140
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Activation of the NLRP3 inflammasome plays an important role in high glucose- induced endothelial dysfunction in patients with type 2 diabetes mellitus (T2DM). | Glucose | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | In the current study, we aimed to investigate whether dulaglutide possesses a protective effect against high glucose- induced activation of the NLRP3 inflammasome. | Glucose | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Dulaglutide suppressed high glucose- induced activation of NLRP3 inflammasome by reducing the expression of NLRP3, ASC, and cleaved caspase 1 (P10). | Glucose | NLR family pyrin domain containing 3 | Homo sapiens |
| 4 | Dulaglutide suppressed high glucose- induced activation of NLRP3 inflammasome by reducing the expression of NLRP3, ASC, and cleaved caspase 1 (P10). | Glucose | NLR family pyrin domain containing 3 | Homo sapiens |