Uric Acid

NLR family pyrin domain containing 3 ; Homo sapiens







110 Article(s)
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1 34875574 Human fetal membrane IL-1β production in response to bacterial components is mediated by uric-acid induced NLRP3 inflammasome activation. 2022 Feb 1
2 35309342 Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis. 2022 1
3 35462936 (-)-Epicatechin Ameliorates Monosodium Urate-Induced Acute Gouty Arthritis Through Inhibiting NLRP3 Inflammasome and the NF-κB Signaling Pathway. 2022 2
4 35464445 Inflammatory Response to Regulated Cell Death in Gout and Its Functional Implications. 2022 2
5 33389490 The roles of NLRP3 inflammasome-mediated signaling pathways in hyperuricemic nephropathy. 2021 Mar 2
6 33505510 Cichoric Acid Ameliorates Monosodium Urate-Induced Inflammatory Response by Reducing NLRP3 Inflammasome Activation via Inhibition of NF-kB Signaling Pathway. 2021 2
7 33547278 Sensing soluble uric acid by Naip1-Nlrp3 platform. 2021 Feb 5 1
8 33677310 Total glucosides of paeony protects THP-1 macrophages against monosodium urate-induced inflammation via MALAT1/miR-876-5p/NLRP3 signaling cascade in gouty arthritis. 2021 Jun 4
9 33746978 Decoy Receptor 3 Inhibits Monosodium Urate-Induced NLRP3 Inflammasome Activation via Reduction of Reactive Oxygen Species Production and Lysosomal Rupture. 2021 3
10 33798500 Gout. 2021 May 15 1
11 33830232 1'-Acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression. 2021 Jun 18 2
12 33902703 Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production. 2021 Apr 26 2
13 33935726 MicroRNA-223 Suppresses IL-1β and TNF-α Production in Gouty Inflammation by Targeting the NLRP3 Inflammasome. 2021 1
14 34053376 Regulation of crystal induced inflammation: current understandings and clinical implications. 2021 Jul 1
15 34390315 The current role of NLRP3 inflammasome polymorphism in gout susceptibility. 2021 Oct 2
16 34831052 NLRP3 Activation and Its Relationship to Endothelial Dysfunction and Oxidative Stress: Implications for Preeclampsia and Pharmacological Interventions. 2021 Oct 21 1
17 34925366 Purinergic Signaling in the Regulation of Gout Flare and Resolution. 2021 2
18 31705795 Allopurinol inhibits excess glucose-induced trophoblast IL-1β and ROS production. 2020 Jan 1
19 31924495 Development of novel NLRP3-XOD dual inhibitors for the treatment of gout. 2020 Feb 15 2
20 31996020 Soluble Uric Acid Promotes Atherosclerosis via AMPK (AMP-Activated Protein Kinase)-Mediated Inflammation. 2020 Mar 1
21 32452918 The role of uric acid in inflammasome-mediated kidney injury. 2020 Jul 4
22 32469177 Ethanol Augments Monosodium Urate-Induced NLRP3 Inflammasome Activation via Regulation of AhR and TXNIP in Human Macrophages. 2020 Jun 7
23 32536991 Association between Nod-like receptor protein 3 inflammasome and gouty nephropathy. 2020 Jul 2
24 32552358 Toll-Like receptor 4 (TLR4) polymorphism rs2149356 and risk of gout in a Spanish cohort. 2020 1
25 32650532 The NLRP3 Inflammasome Role in the Pathogenesis of Pregnancy Induced Hypertension and Preeclampsia. 2020 Jul 8 1
26 32695290 Soluble uric acid induces inflammation via TLR4/NLRP3 pathway in intestinal epithelial cells. 2020 Jun 5
27 33131902 Bruton's Tyrosine Kinase Inhibitor Attenuates Warm Hepatic Ischemia/Reperfusion Injury via Modulation of the NLR Family Pyrin Domain Containing 3 Inflammasome. 2020 Dec 1
28 29385859 The NLRP3 rs10754558 polymorphism is a risk factor for preeclampsia in a Chinese Han population. 2019 Jun 1
29 30347231 LncRNA ANRIL promotes NLRP3 inflammasome activation in uric acid nephropathy through miR-122-5p/BRCC3 axis. 2019 Feb 1
30 30591286 Why Colchicine Should Be Considered for Secondary Prevention of Atherosclerosis: An Overview. 2019 Jan 1
31 30612459 Rhein, An Anthraquinone Drug, Suppresses the NLRP3 Inflammasome and Macrophage Activation in Urate Crystal-Induced Gouty Inflammation. 2019 1
32 30637441 Suppression of Syk activation by resveratrol inhibits MSU crystal-induced inflammation in human monocytes. 2019 Mar 2
33 30728075 Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression. 2019 Feb 6 1
34 30807742 The role of lysosomal cysteine cathepsins in NLRP3 inflammasome activation. 2019 Jul 30 2
35 30824640 Precipitation of Soluble Uric Acid Is Necessary for In Vitro Activation of the NLRP3 Inflammasome in Primary Human Monocytes. 2019 Sep 7
36 30833078 TXNIP-mediated nuclear factor-κB signaling pathway and intracellular shifting of TXNIP in uric acid-induced NLRP3 inflammasome. 2019 Apr 16 5
37 31189953 Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome. 2019 Jun 1
38 31357788 [Role of NLRP3 inflammasome in the pathogenesis of alcoholic liver disease]. 2019 Jul 20 1
39 31358323 Anti-inflammatory effect of artemisinin on uric acid-induced NLRP3 inflammasome activation through blocking interaction between NLRP3 and NEK7. 2019 Sep 17 6
40 31412804 Uric acid regulates NLRP3/IL-1β signaling pathway and further induces vascular endothelial cells injury in early CKD through ROS activation and K+ efflux. 2019 Aug 14 5
41 31649546 Inflammation in Renal Diseases: New and Old Players. 2019 1
42 31707403 Elevated Uric Acid Levels Promote Vascular Smooth Muscle Cells (VSMC) Proliferation via an Nod-Like Receptor Protein 3 (NLRP3)-Inflammasome-Dependent Mechanism. 2019 Nov 10 7
43 31819864 Calcium Pyrophosphate And Monosodium Urate Activate The NLRP3 Inflammasome Within Bladder Urothelium Via Reactive Oxygen Species And TXNIP. 2019 2
44 33693087 Hyperuricemia as a Risk Factor for Atrial Fibrillation Due to Soluble and Crystalized Uric Acid. 2019 Nov 1 1
45 28880687 TNF-α potentiates uric acid-induced interleukin-1β (IL-1β) secretion in human neutrophils. 2018 May 1
46 29214547 Association of NLRP3 polymorphisms with susceptibility to primary gouty arthritis in a Chinese Han population. 2018 Jan 2
47 29247992 Metabolic regulation of NLRP3. 2018 Jan 1
48 29415757 Soluble uric acid increases PDZK1 and ABCG2 expression in human intestinal cell lines via the TLR4-NLRP3 inflammasome and PI3K/Akt signaling pathway. 2018 Feb 7 3
49 29683202 Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts. 2018 Jul 1
50 29780394 Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis. 2018 3