Title : Why Colchicine Should Be Considered for Secondary Prevention of Atherosclerosis: An Overview.

Pub. Date : 2019 Jan

PMID : 30591286






1 Functional Relationships(s)
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1 Recent demonstration that cholesterol crystals trigger the NLRP3 (nucleotide oligomerization domain-, leucine-rich repeat-, and pyrin domain-containing protein 3) inflammasome and the release of inflammatory cytokines that also drive uric acid crystal-induced inflammation indicates that the multiple actions of colchicine that make it effective in gout may be relevant to preventing inflammation and limiting inflammatory injury in atherosclerosis. Uric Acid NLR family pyrin domain containing 3 Homo sapiens