Letrozole

estrogen receptor 1 ; Homo sapiens







75 Article(s)
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1 35363275 Phase Ib/II Dose Expansion Study of Lenvatinib Combined with Letrozole in Postmenopausal Women with Hormone Receptor-Positive Breast Cancer. 2022 Jun 1 1
2 35524184 Maintenance Therapy with Aromatase Inhibitor in epithelial Ovarian Cancer (MATAO): study protocol of a randomized double-blinded placebo-controlled multi-center phase III Trial. 2022 May 6 1
3 33528846 KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery. 2021 Apr 2
4 33818022 Clinical Outcomes Following Letrozole Treatment according to Estrogen Receptor Expression in Postmenopausal Women: LETTER Study (KBCSG-006). 2021 Apr 4
5 33920789 MicroRNAs and Long Noncoding RNAs as Novel Therapeutic Targets in Estrogen Receptor-Positive Breast and Ovarian Cancers. 2021 Apr 15 2
6 34032767 Long-term response on letrozole for gastric cancer: A case report. 2021 May 28 1
7 34267813 Mammospheres of letrozole-resistant breast cancer cells enhance breast cancer aggressiveness. 2021 Aug 1
8 34356536 Role of Persistent Organic Pollutants in Breast Cancer Progression and Identification of Estrogen Receptor Alpha Inhibitors Using In-Silico Mining and Drug-Drug Interaction Network Approaches. 2021 Jul 19 1
9 31727690 Estrogen Receptor Pathway Activity Score to Predict Clinical Response or Resistance to Neoadjuvant Endocrine Therapy in Primary Breast Cancer. 2020 Feb 1
10 32125937 Phase II Single-Arm Study of Preoperative Letrozole for Estrogen Receptor-Positive Postmenopausal Ductal Carcinoma In Situ: CALGB 40903 (Alliance). 2020 Apr 20 2
11 32151708 Changes in serum estrogenic activity during neoadjuvant therapy with letrozole and exemestane. 2020 Jun 2
12 32683565 Overall survival results from the randomized phase 2 study of palbociclib in combination with letrozole versus letrozole alone for first-line treatment of ER+/HER2- advanced breast cancer (PALOMA-1, TRIO-18). 2020 Sep 1
13 32713085 Ribociclib therapy in peritoneal carcinomatosis secondary to HER2-negative metastatic breast cancer: A clinical case with a positive outcome. 2020 Sep 1
14 32988919 Predictive Role of TP53, PIK3CA and MLL2 in ER+ HER2+ Breast Bancer: Biomarker Analysis of Neo-ALL-IN [NCT 01275859]. 2020 Oct 1
15 31092464 The Role of Previous Therapies and Sites of Metastasis as Influencing Factors on Discordance of ER, PR and HER2 Status Between Primary and Metastasized Breast Cancer. 2019 May 1
16 31217344 Palbociclib with Letrozole in Postmenopausal Women with ER+/HER2- Advanced Breast Cancer: Hematologic Safety Analysis of the Randomized PALOMA-2 Trial. 2019 Dec 1
17 29157627 Letrozole may be a valuable maintenance treatment in high-grade serous ovarian cancer patients. 2018 Jan 1
18 29168427 Neoadjuvant letrozole for postmenopausal estrogen receptor-positive, HER2-negative breast cancer patients, a study from the Danish Breast Cancer Cooperative Group (DBCG). 2018 Jan 1
19 29337187 Metabolomics Reveals that Dietary Xenoestrogens Alter Cellular Metabolism Induced by Palbociclib/Letrozole Combination Cancer Therapy. 2018 Mar 15 2
20 29581135 ER+ Breast Cancers Resistant to Prolonged Neoadjuvant Letrozole Exhibit an E2F4 Transcriptional Program Sensitive to CDK4/6 Inhibitors. 2018 Jun 1 1
21 29733541 A multicenter phase II trial of neoadjuvant letrozole plus low-dose cyclophosphamide in postmenopausal patients with estrogen receptor-positive breast cancer (JBCRG-07): therapeutic efficacy and clinical implications of circulating endothelial cells. 2018 Jun 2
22 28163101 Identification of miRNAs as biomarkers for acquired endocrine resistance in breast cancer. 2017 Nov 15 3
23 28643023 Variable aromatase inhibitor plasma concentrations do not correlate with circulating estrogen concentrations in post-menopausal breast cancer patients. 2017 Oct 4
24 28794284 Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance. 2017 Aug 9 1
25 28842253 Repression of ESR1 transcription by MYOD potentiates letrozole-resistance in ERα-positive breast cancer cells. 2017 Oct 21 6
26 28856074 Utilizing Tumor and Plasma Liquid Biopsy in Treatment Decision Making for an Estrogen Receptor-Positive Advanced Breast Cancer Patient. 2017 Jun 29 2
27 28978004 Detection of ESR1 mutations in circulating cell-free DNA from patients with metastatic breast cancer treated with palbociclib and letrozole. 2017 Sep 15 2
28 29070044 Neoadjuvant everolimus plus letrozole versus fluorouracil, epirubicin and cyclophosphamide for ER-positive, HER2-negative breast cancer: study protocol for a randomized pilot trial. 2017 Oct 25 2
29 29291017 miR-1271 inhibits ERα expression and confers letrozole resistance in breast cancer. 2017 Dec 5 2
30 27009458 Hyperuricemia in 2 Patients Receiving Palbociclib for Breast Cancer. 2016 Jan 1
31 27491481 Phase II trial of neoadjuvant letrozole and lapatinib in Asian postmenopausal women with estrogen receptor (ER) and human epidermal growth factor receptor 2 (HER2)-positive breast cancer [Neo-ALL-IN]: Highlighting the TILs, ER expressional change after neoadjuvant treatment, and FES-PET as potential significant biomarkers. 2016 Oct 2
32 28118723 [Treatment with Aromatase Inhibitors in Postmenopausal Women with Breast Cancer and the Possibility of Influencing Side Effects]. 2016 Fall 1
33 25695958 Preclinical pharmacological evaluation of letrozole as a novel treatment for gliomas. 2015 Apr 1
34 26536870 Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover. 2015 Nov 1
35 26590813 ESR1 and ESR2 polymorphisms in the BIG 1-98 trial comparing adjuvant letrozole versus tamoxifen or their sequence for early breast cancer. 2015 Dec 3
36 24472707 Nonhypoxic regulation and role of hypoxia-inducible factor 1 in aromatase inhibitor resistant breast cancer. 2014 Jan 29 1
37 24663045 Stand up to cancer phase Ib study of pan-phosphoinositide-3-kinase inhibitor buparlisib with letrozole in estrogen receptor-positive/human epidermal growth factor receptor 2-negative metastatic breast cancer. 2014 Apr 20 1
38 24725461 Articular cartilage chondrocytes express aromatase and use enzymes involved in estrogen metabolism. 2014 Apr 11 2
39 25421542 Effects of zoledronic acid and the association between its efficacy and γδT cells in postmenopausal women with breast cancer treated with preoperative hormonal therapy: a study protocol. 2014 Nov 25 1
40 23704778 Proteomic signatures of acquired letrozole resistance in breast cancer: suppressed estrogen signaling and increased cell motility and invasiveness. 2013 Sep 1
41 23980056 The effect of letrozole with misoprostol for medical termination of pregnancy on the expression of steroid receptors in the placenta. 2013 Nov 3
42 24213953 Tamoxifen or letrozole versus standard methods for women with estrogen-receptor positive breast cancer undergoing oocyte or embryo cryopreservation in assisted reproduction. 2013 Nov 8 1
43 22550166 AIB1:ERα transcriptional activity is selectively enhanced in aromatase inhibitor-resistant breast cancer cells. 2012 Jun 15 4
44 22802308 Suppression of plasma estrogen levels by letrozole and anastrozole is related to body mass index in patients with breast cancer. 2012 Aug 20 1
45 21245100 Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole. 2011 Mar 1 2
46 21413907 Aromatase inhibition: a potential target for the management of recurrent or metastatic endometrial cancer by letrozole: more questions than answers? 2011 May 1
47 21555689 Randomized phase II neoadjuvant comparison between letrozole, anastrozole, and exemestane for postmenopausal women with estrogen receptor-rich stage 2 to 3 breast cancer: clinical and biomarker outcomes and predictive value of the baseline PAM50-based intrinsic subtype--ACOSOG Z1031. 2011 Jun 10 1
48 21870129 Invasive lobular carcinoma: response to neoadjuvant letrozole therapy. 2011 Dec 4
49 21916582 Autophagy and endocrine resistance in breast cancer. 2011 Aug 1
50 22006739 Lapatinib in the treatment of HER-2 overexpressing breast cancer. 2011 Jul-Sep 2