Title : Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.

Pub. Date : 2017 Aug 9

PMID : 28794284






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RNA sequencing of letrozole-treated tumors revealed the existence of intrachromosomal ESR1 fusion transcripts and increased expression of gene signatures indicative of enhanced E2F-mediated transcription and cell cycle processes in cancers with high Ki67. Letrozole estrogen receptor 1 Homo sapiens