Genistein

estrogen receptor 1 ; Homo sapiens







116 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34673318 Elucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells. 2022 Jan 1
2 34801523 Developmental exposure to phytoestrogens found in soy: New findings and clinical implications. 2022 Jan 1
3 33853499 Genistein Triggers Translocation of Estrogen Receptor-Alpha in Mitochondria to Induce Expressions of ATP Synthesis-Associated Genes and Improves Energy Production and Osteoblast Maturation. 2021 2
4 34209224 Current Perspectives on the Beneficial Effects of Soybean Isoflavones and Their Metabolites for Humans. 2021 Jun 30 1
5 34505520 Genistein does not inhibit TGF-beta1-induced conversion of human dermal fibroblasts to myofibroblasts. 2021 Nov 29 1
6 34836271 Genistein Regulates Lipid Metabolism via Estrogen Receptor β and Its Downstream Signal Akt/mTOR in HepG2 Cells. 2021 Nov 10 3
7 29171786 Bidirectional regulation of genistein on the proliferation and differentiation of C2C12 myoblasts. 2020 Nov 1
8 32926937 Dietary isoflavone-induced, estrogen receptor-β-mediated proliferation of Caco-2 cells is modulated by gallic acid. 2020 Nov 1
9 32945668 SAR Study on Estrogen Receptor α/β Activity of (Iso)flavonoids: Importance of Prenylation, C-Ring (Un)Saturation, and Hydroxyl Substituents. 2020 Sep 30 1
10 33070824 [Roles of G protein-coupled receptor 30 in the effects of genistein on apoptosis and cell cycle in human thyroid squamous cells SW579]. 2020 Sep 1
11 33209217 Effect of 5-aza-2'-deoxycytidine on Estrogen Receptor Alpha/Beta and DNA Methyltransferase 1 Genes Expression, Apoptosis Induction, and Cell Growth Prevention of the Colon Cancer HT 29 Cell Line. 2020 1
12 30352359 Dual effects of isoflavonoids from Pueraria lobata roots on estrogenic activity and anti-proliferation of MCF-7 human breast carcinoma cells. 2019 Mar 1
13 30737644 ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway. 2019 Jun 5
14 30883882 Estrogen receptor genes polymorphisms determine serum lipid profile in healthy postmenopausal women treated with calcium, vitamin D, and genistein. 2019 Aug 1
15 30889096 Safety and feasibility of estrogen receptor-β targeted phytoSERM formulation for menopausal symptoms: phase 1b/2a randomized clinical trial. 2019 Aug 2
16 30945577 The phytoestrogen genistein affects inflammatory-related genes expression depending on the ERα/ERβ ratio in breast cancer cells. 2019 Dec 4
17 29636868 Novasoy and genistein inhibit endometrial cancer cell proliferation through disruption of the AKT/mTOR and MAPK signaling pathways. 2018 1
18 29743815 Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer. 2018 1
19 29861831 Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches. 2018 1
20 29963755 Soy-Derived Phytochemical Genistein Modifies Chromatome Topology to Restrict Cancer Cell Proliferation. 2018 Aug 1
21 28842010 A novel high throughput screening assay for binding affinities of perfluoroalkyl iodide for estrogen receptor alpha and beta isoforms. 2017 Dec 1 1
22 29051735 The Impacts of Genistein and Daidzein on Estrogen Conjugations in Human Breast Cancer Cells: A Targeted Metabolomics Approach. 2017 1
23 29286617 Genistein and Trichostatin A Induction of Estrogen Receptor Alpha Gene Expression, Apoptosis and Cell Growth Inhibition in Hepatocellular Carcinoma HepG 2 Cells 2017 Dec 29 2
24 26100284 The Phytoestrogen Genistein Affects Breast Cancer Cells Treatment Depending on the ERα/ERβ Ratio. 2016 Jan 4
25 26794366 Genistein-induced differentiation of breast cancer stem/progenitor cells through a paracrine mechanism. 2016 Mar 3
26 27156127 Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens. 2016 Sep 2
27 27582276 Epigenetic regulation of transcription factor promoter regions by low-dose genistein through mitogen-activated protein kinase and mitogen-and-stress activated kinase 1 nongenomic signaling. 2016 Aug 31 2
28 25136773 Genistein disrupts glucocorticoid receptor signaling in human uterine endometrial Ishikawa cells. 2015 Jan 1
29 26361015 The effect of glucuronidation on isoflavone induced estrogen receptor (ER)α and ERβ mediated coregulator interactions. 2015 Nov 2
30 26407941 Genistein suppressed epithelial-mesenchymal transition and migration efficacies of BG-1 ovarian cancer cells activated by estrogenic chemicals via estrogen receptor pathway and downregulation of TGF-β signaling pathway. 2015 Oct 15 1
31 24375531 Genistein modulates proliferation and mitochondrial functionality in breast cancer cells depending on ERalpha/ERbeta ratio. 2014 May 3
32 25009600 Genistein inhibits the proliferation and differentiation of MCF-7 and 3T3-L1 cells via the regulation of ERα expression and induction of apoptosis. 2014 Aug 1
33 25078314 Design and synthesis of azaisoflavone analogs as phytoestrogen mimetics. 2014 Oct 6 1
34 25165122 Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line. 2014 Oct 1
35 25493176 Effect of soy isoflavones on the growth of human breast tumors: findings from preclinical studies. 2014 Nov 1
36 23337939 Antiproliferative activity of daidzein and genistein may be related to ERα/c-erbB-2 expression in human breast cancer cells. 2013 Mar 6
37 23384675 Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes. 2013 Apr 1
38 23682706 Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells. 2013 Jul 15 1
39 23871935 Genistein modulates oxidative stress in breast cancer cell lines according to ERα/ERβ ratio: effects on mitochondrial functionality, sirtuins, uncoupling protein 2 and antioxidant enzymes. 2013 Sep 4
40 24284485 Genistein enhances the radiosensitivity of breast cancer cells via G₂/M cell cycle arrest and apoptosis. 2013 Oct 24 2
41 22504913 Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. 2012 Apr 3
42 23019147 Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner. 2012 Nov 1
43 20884965 Quantitative proteomics and transcriptomics addressing the estrogen receptor subtype-mediated effects in T47D breast cancer cells exposed to the phytoestrogen genistein. 2011 Jan 2
44 21056929 Isoflavones suppress cyclic adenosine 3',5'-monophosphate regulatory element-mediated transcription in osteoblastic cell line. 2011 Sep 2
45 21160418 Additive effects of trastuzumab and genistein on human breast cancer cells. 2011 Mar 1
46 21389782 Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer. 2011 May 15 5
47 21624456 Genistein impairs early testosterone production in fetal mouse testis via estrogen receptor alpha. 2011 Dec 1
48 22052998 In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. 2011 Dec 2
49 19427779 Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-alpha-mediated transcription in MCF-7 breast cancer cells. 2010 May 3
50 20387803 Measuring binding kinetics of ligands with tethered receptors by fluorescence polarization and total internal reflection fluorescence. 2010 May 1 1