Disulfides

alpha-2-macroglobulin ; Homo sapiens







35 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33964423 Structural Investigations of Human A2M Identify a Hollow Native Conformation That Underlies Its Distinctive Protease-Trapping Mechanism. 2021 2
2 33291690 Multiple Disulfide-Bonded States of Native Proteins: Estimate of Number Using Probabilities of Disulfide Bond Formation. 2020 Dec 4 2
3 33301305 Substituting the Thiol Ester of Human A2M or C3 with a Disulfide Produces Native Proteins with Altered Proteolysis-Induced Conformational Changes. 2020 Dec 29 2
4 25900303 Fibroblastic synoviocytes secrete plasma proteins via α2 -macroglobulins serving as intracellular and extracellular chaperones. 2015 Nov 2
5 15910735 Mutation of lysine 1370 in full-length human alpha2-macroglobulin blocks binding to the low density lipoprotein receptor-related protein-1. 2005 Jun 1 1
6 12147353 New member of the trefoil factor family of proteins is an alpha-macroglobulin protease inhibitor. 2002 Jul 29 2
7 12218066 Localization of carbohydrate attachment sites and disulfide bridges in limulus alpha 2-macroglobulin. Evidence for two forms differing primarily in their bait region sequences. 2002 Nov 15 3
8 8620037 Preparation and characterization of a C-terminal fragment of pregnancy zone protein corresponding to the receptor-binding peptide from human alpha 2-macroglobulin. 1996 Apr 16 1
9 8806751 The conformational state of human alpha 2-macroglobulin influences its dissociation into half-molecules by sodium thiocyanate. 1996 Sep 1 1
10 7539801 Alpha 2-macroglobulin bait region variants. A role for the bait region in tetramer formation. 1995 Jun 9 2
11 7508448 Oxidative dissociation of human alpha 2-macroglobulin tetramers into dysfunctional dimers. 1994 Feb 11 1
12 7509297 Thiol ester role in correct folding and conformation of human alpha 2-macroglobulin. Properties of recombinant C949S variant. 1994 Feb 21 1
13 7514405 The role of cysteine-949 in the binding of transforming growth factor-beta 1 and transforming growth factor-beta 2 to alpha 2-macroglobulin. 1994 May 16 1
14 7524419 Disulfide bond formation by methanethiolation of the thiol ester sulfhydryl group of alpha 2M. 1994 Sep 10 1
15 7688570 Epidermal growth factor binding to human alpha 2-macroglobulin. Implications for alpha 2-macroglobulin-growth factor interactions. 1993 Aug 10 1
16 1377675 Reversible binding of platelet-derived growth factor-AA, -AB, and -BB isoforms to a similar site on the "slow" and "fast" conformations of alpha 2-macroglobulin. 1992 Jun 25 1
17 1705175 Covalent binding of human alpha 2-macroglobulin to deglycosylated ricin A chain and its immunotoxins. 1991 Mar 1 1
18 1712069 Covalent disulfide binding of human IL-1 beta to alpha 2-macroglobulin: inhibition by D-penicillamine. 1991 Apr-May 3
19 1721638 Reduction of disulfide bonds within lysosomes is a key step in antigen processing. 1991 Dec 15 1
20 1692242 Inhibition and partial reversal of the methylamine-induced conversion of "slow" to "fast" electrophoretic forms of human alpha 2-macroglobulin by modification of the thiols. 1990 Feb 13 1
21 1698779 Localization of epsilon-lysyl-gamma-glutamyl cross-links in five human alpha 2-macroglobulin-proteinase complexes. Nature of the high molecular weight cross-linked products. 1990 Oct 15 2
22 2466831 Identification of alpha 2-macroglobulin as a cytokine binding plasma protein. Binding of interleukin-1 beta to "F" alpha 2-macroglobulin. 1989 Apr 5 1
23 2469470 A conserved region in alpha-macroglobulins participates in binding to the mammalian alpha-macroglobulin receptor. 1989 Feb 7 1
24 2752977 High molecular weight forms of placental lactogen: evidence for lactogen-macroglobulin complexes in rodents and humans. 1989 Aug 2
25 2452651 Subunits of human alpha 2-macroglobulin produced by specific reduction of interchain disulfide bonds with thioredoxin. 1988 Feb 9 7
26 2443487 A mouse monoclonal antibody to human alpha 2-macroglobulin (alpha 2M) crossreacts with alpha 2M from mouse: epitope mapping and characterization of subunit structure of murine alpha 2M. 1987 May 1
27 2447879 Functional alpha 2-macroglobulin half-molecules induced by cadmium. 1987 Dec 16 1
28 2420357 Purification and characterization of a "half-molecule" alpha 2-macroglobulin from the southern grass frog: absence of binding to the mammalian alpha 2-macroglobulin receptor. 1986 Feb 11 1
29 2430963 Primary structure of human alpha 2-macroglobulin. Complete disulfide bridge assignment and localization of two interchain bridges in the dimeric proteinase binding unit. 1986 Dec 5 5
30 2416557 Characterization of a half-molecular fragment obtained by reduction of human alpha 2-macroglobulin with dithiothreitol. A small-angle X-ray and neutron scattering investigation. 1985 2
31 6198647 Specific covalent binding of platelet-derived growth factor to human plasma alpha 2-macroglobulin. 1984 Jan 1
32 6203904 Primary structure of human alpha 2-macroglobulin. I. Isolation of the 26 CNBr fragments, amino acid sequence of 13 small CNBr fragments, amino acid sequence of methionine-containing peptides, and alignment of all CNBr fragments. 1984 Jul 10 1
33 6203906 Primary structure of human alpha 2-macroglobulin. III. Primary structure of three large disulfide-bridged CNBr fragments, located in the COOH-terminal part of alpha 2-macroglobulin and accounting for 301 residues. 1984 Jul 10 2
34 6437445 Formation of a stable complex of thrombin and the secreted platelet protein glycoprotein G (thrombin-sensitive protein, thrombospondin) by thiol-disulfide exchange. 1984 Oct 9 1
35 4269559 Studies on human plasma alpha 2-macroglobulin-enzyme interactions. Evidence for proteolytic modification of the subunit chain structure. 1973 Sep 1 1