Pub. Date : 1995 Jun 9
PMID : 7539801
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These findings indicate that residues in the bait region appear to be necessary for noncovalent association of 360-kDa disulfide-linked dimers to give tetrameric alpha 2M and suggest a role for the bait region in normal alpha 2M in coupling bait region cleavage to the sequence of conformational changes that result in thiol ester activation and ultimately proteinase trapping. | Disulfides | alpha-2-macroglobulin | Homo sapiens |
| 2 | These findings indicate that residues in the bait region appear to be necessary for noncovalent association of 360-kDa disulfide-linked dimers to give tetrameric alpha 2M and suggest a role for the bait region in normal alpha 2M in coupling bait region cleavage to the sequence of conformational changes that result in thiol ester activation and ultimately proteinase trapping. | Disulfides | alpha-2-macroglobulin | Homo sapiens |