Paclitaxel

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







381 Article(s)
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301 17189388 Peptide aptamers with binding specificity for the intracellular domain of the ErbB2 receptor interfere with AKT signaling and sensitize breast cancer cells to Taxol. 2006 Dec 1
302 17212145 [A case of advanced breast cancer with meningeal carcinomas and orbital metastasis successfully treated with multi-disciplinary therapy]. 2006 Nov 2
303 20859353 Phase II Trial of a Novel Paclitaxel Schedule As Single-Agent, First-Line Therapy for HER-2/neu-Negative Metastatic Breast Cancer: A Community-Based Study. 2006 Nov 4
304 15668276 Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate. 2005 Feb 2
305 15700118 Inhibition of HER-2 by three independent targeting strategies increases paclitaxel resistance of SKOV-3 ovarian carcinoma cells. 2005 Feb 8
306 15738535 Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. 2005 Jun 1 1
307 15941387 HER2-mediated internalization of a targeted prodrug cytotoxic conjugate is dependent on the valency of the targeting ligand. 2005 Jun 4
308 16110294 Pathological complete response to trastuzumab and paclitaxel in a patient with inflammatory local recurrence following breast conserving surgery. 2005 1
309 16115903 Breast cancer molecular subtypes respond differently to preoperative chemotherapy. 2005 Aug 15 1
310 16173788 Combined radioimmunotherapy and chemotherapy of breast tumors with Y-90-labeled anti-Her2 and anti-CEA antibodies with taxol. 2005 Sep-Oct 1
311 16216740 Response of bilateral choroidal metastases of breast cancer to therapy with trastuzumab. 2005 Oct 2
312 16360542 Gemcitabine-taxane experience in the treatment of metastatic breast cancer. 2005 1
313 16361156 [Therapeutic effect of TAX combined with Herceptin or epirubicin against breast cancer positive for Her-2/neu]. 2005 Dec 3
314 16381626 Two concurrent phase II trials of paclitaxel/carboplatin/trastuzumab (weekly or every-3-week schedule) as first-line therapy in women with HER2-overexpressing metastatic breast cancer: NCCTG study 983252. 2005 Dec 2
315 14710203 Phase II study of weekly paclitaxel and trastuzumab in anthracycline- and taxane-pretreated patients with HER2-overexpressing metastatic breast cancer. 2004 Jan 12 3
316 15034952 Trastuzumab in the treatment of advanced breast cancer. Our single-center experience and spotlights of the latest national consensus meeting. 2004 1
317 15059359 [Effect of Herceptin combined with Taxol on patients with Her-2/neu overexpressing metastatic breast cancer]. 2004 Jan 3
318 15117984 Phase II trial of trastuzumab followed by weekly paclitaxel/carboplatin as first-line treatment for patients with metastatic breast cancer. 2004 May 1 1
319 15123142 [Indications for Herceptin in breast cancer treatment]. 2004 Feb 1
320 15161043 Serum HER-2/neu as a prediction and monitoring parameter in a phase II study with weekly paclitaxel in metastatic breast cancer. 2004 Mar-Apr 2
321 15217493 Doxorubicin and paclitaxel enhance the antitumor efficacy of vaccines directed against HER 2/neu in a murine mammary carcinoma model. 2004 1
322 15292386 Her-2/neu gene amplification and response to paclitaxel in patients with metastatic breast cancer. 2004 Aug 4 1
323 15501983 Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells. 2004 Oct 15 1
324 15581045 Paclitaxel and gemcitabine, as first-line chemotherapy, combined with trastuzumab in patients with advanced breast cancer: a phase II study conducted by the Hellenic Cooperative Oncology Group (HeCOG). 2004 1
325 15582895 4-years results of weekly trastuzumab and paclitaxel in the treatment of women with HER2/neu overexpressing advanced breast cancer: single institution prospective study. 2004 Oct 2
326 12506169 Preoperative therapy with trastuzumab and paclitaxel followed by sequential adjuvant doxorubicin/cyclophosphamide for HER2 overexpressing stage II or III breast cancer: a pilot study. 2003 Jan 1 1
327 12576925 Decreased response to paclitaxel versus docetaxel in HER-2/neu transfected human breast cancer cells. 2003 Feb 3
328 12603385 Central nervous system progression during systemic response to trastuzumab, humanized anti-HER-2/neu antibody, plus paclitaxel in a woman with refractory metastatic breast cancer. 2003 Mar-Apr 1
329 12680177 Prolonged administration of weekly paclitaxel and trastuzumab in patients with advanced breast cancer. 2003 Jan-Feb 2
330 12722021 Gemcitabine combined with paclitaxel or paclitaxel/trastuzumab in metastatic breast cancer. 2003 Apr 1
331 12724856 Targeted prodrug treatment of HER-2-positive breast tumor cells using trastuzumab and paclitaxel linked by A-Z-CINN Linker. 2003 Jan-Feb 1
332 12761490 HER2/PI-3K/Akt activation leads to a multidrug resistance in human breast adenocarcinoma cells. 2003 May 22 1
333 12973835 ErbB2 overexpression in human breast carcinoma is correlated with p21Cip1 up-regulation and tyrosine-15 hyperphosphorylation of p34Cdc2: poor responsiveness to chemotherapy with cyclophoshamide methotrexate, and 5-fluorouracil is associated with Erb2 overexpression and with p21Cip1 overexpression. 2003 Sep 15 2
334 14507946 Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel. 2003 Nov 1 1
335 14676119 Pilot trial of trastuzumab starting with or after the doxorubicin component of a doxorubicin plus paclitaxel regimen for women with HER2-positive advanced breast cancer. 2003 Dec 1 1
336 14768403 Gemcitabine, paclitaxel, and trastuzumab in metastatic breast cancer. 2003 Dec 1
337 11790161 Trastuzumab: a review of its use in the treatment of metastatic breast cancer overexpressing HER2. 2002 1
338 11872285 Low HER2/neu gene expression is associated with pathological response to concurrent paclitaxel and radiation therapy in locally advanced breast cancer. 2002 Feb 1 1
339 11881914 Factors associated with success of the extreme drug resistance assay in primary breast cancer specimens. 2002 Jan 1
340 12049736 Phosphorylation on tyrosine-15 of p34(Cdc2) by ErbB2 inhibits p34(Cdc2) activation and is involved in resistance to taxol-induced apoptosis. 2002 May 3
341 12138396 Trastuzumab/chemotherapy combinations in metastatic breast cancer. 2002 Jun 1
342 12209684 Does HER2/neu expression provide prognostic information in patients with advanced urothelial carcinoma? 2002 Sep 1 2
343 12384528 Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells. 2002 Oct 15 11
344 12419746 In vitro comparative evaluation of trastuzumab (Herceptin) combined with paclitaxel (Taxol) or docetaxel (Taxotere) in HER2-expressing human breast cancer cell lines. 2002 Nov 5
345 11208823 Response to cyclophosphamide, methotrexate, and fluorouracil in lymph node-positive breast cancer according to HER2 overexpression and other tumor biologic variables. 2001 Jan 15 1
346 11352950 Weekly trastuzumab and paclitaxel therapy for metastatic breast cancer with analysis of efficacy by HER2 immunophenotype and gene amplification. 2001 May 15 2
347 11464447 From HER2 to herceptin. 2001 1
348 11477443 HER-2 expression is a prognostic factor in patients with metastatic breast cancer treated with a combination of high-dose cyclophosphamide, mitoxantrone, paclitaxel and autologous blood stem cell support. 2001 Apr 2
349 11496337 Pharmacokinetic and biochemical analysis in the treatment of weekly paclitaxel in relapsed breast cancer. 2001 Sep-Oct 3
350 11521725 Ongoing trials with trastuzumab in metastatic breast cancer. 2001 3