Oligonucleotides

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







46 Article(s)
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1 35282632 Site-specific DNA functionalization through the tetrazene-forming reaction in ionic liquids. 2022 Feb 9 1
2 32526138 Development of a Versatile and Modular Linker for Antibody-Drug Conjugates Based on Oligonucleotide Strand Pairing. 2020 Jul 15 1
3 30991278 An oligonucleotide probe incorporating the chromophore of green fluorescent protein is useful for the detection of HER-2 mRNA breastĀ cancer marker. 2019 Jul 1 3
4 31608694 Silencing Breast Cancer Genes Using Morpholino Embedded DNA-Tile-AuNPs Nanostructures. 2019 Dec 1
5 29655990 Inorganic kernel - Supported asymmetric hybrid vesicles for targeting delivery of STAT3-decoy oligonucleotides to overcome anti-HER2 therapeutic resistance of BT474R. 2018 Jun 10 1
6 29887936 Rapid micro fluorescence in situ hybridization in tissue sections. 2018 Jul 1
7 27520726 HER2-positive breast cancer targeting and treatment by a peptide-conjugated mini nanodrug. 2017 Feb 2
8 26930249 Current development of targeted oligonucleotide-based cancer therapies: Perspective on HER2-positive breast cancer treatment. 2016 Apr 1
9 23395887 Downregulation of HER3 by a novel antisense oligonucleotide, EZN-3920, improves the antitumor activity of EGFR and HER2 tyrosine kinase inhibitors in animal models. 2013 Apr 1
10 22454063 Antisense-mediated exon skipping to shift alternative splicing to treat cancer. 2012 3
11 19035464 Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells. 2009 Feb 15 2
12 19228734 Mitotic deregulation by survivin in ErbB2-overexpressing breast cancer cells contributes to Taxol resistance. 2009 Feb 15 1
13 19259095 Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome. 2009 Mar 10 4
14 19317258 Inhibitory effects of c-erbB-2 antisense oligonucleotide transfection on uterine endometrial cancer Ishikawa cell lines. 2009 1
15 16166319 Bcl-2 antisense oligonucleotide overcomes resistance to E1A gene therapy in a low HER2-expressing ovarian cancer xenograft model. 2005 Sep 15 1
16 14726684 Pharmacodynamic behavior of liposomal antisense oligonucleotides targeting Her-2/neu and vascular endothelial growth factor in an ascitic MDA435/LCC6 human breast cancer model. 2004 Feb 2
17 15017081 Selection of peptides for specific delivery of oligonucleotides into cancer cells. 2004 1
18 15104891 Rapid screening method for antisense oligonucleotides against human growth factor receptor p185(erbB-2). 2004 Spring 2
19 15570009 Trastuzumab down-regulates Bcl-2 expression and potentiates apoptosis induction by Bcl-2/Bcl-XL bispecific antisense oligonucleotides in HER-2 gene--amplified breast cancer cells. 2004 Nov 15 1
20 23077754 LTVSPWY peptide–modified PEGylated chitosan magnetic nanoparticles 2004 4
21 12632082 Antisense Bcl-2 and HER-2 oligonucleotide treatment of breast cancer cells enhances their sensitivity to anticancer drugs. 2003 Apr 1
22 14751825 HER-2-targeted antisense oligonucleotide results in sensitization of head and neck cancer cells to chemotherapeutic agents. 2003 Dec 3
23 12238811 Direct measurement of the association constant of HER2/neu antisense oligonucleotide to its target RNA sequence using a molecular beacon. 2002 Aug 2
24 12435858 Tumor-targeting, systemically delivered antisense HER-2 chemosensitizes human breast cancer xenografts irrespective of HER-2 levels. 2002 Aug 4
25 11399867 Increased sensitivity to cisplatin in gastric cancer by antisense inhibition of the her-2/neu (c-erbB-2) gene. 2001 Jul-Aug 4
26 11687896 Inhibitory effects of the combination of HER-2 antisense oligonucleotide and chemotherapeutic agents used for the treatment of human breast cancer. 2001 Oct 2
27 11726697 Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif. 2001 Dec 1 1
28 21340838 c-erbB-2 Antisense Oligonucleotides Inhibit Serum-Induced Cell Spreading of Ovarian Cancer Cells. 2001 1
29 10699953 Resistance to taxanes is induced by c-erbB-2 overexpression in human MCF-10A mammary epithelial cells and is blocked by combined treatment with an antisense oligonucleotide targeting type I protein kinase A. 2000 Mar 1 1
30 10938266 Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer. 2000 Oct 27 1
31 11079160 Ethanol enhances erbB-mediated migration of human breast cancer cells in culture. 2000 Sep 1
32 11156527 HER2/neu antisense targeting of human breast carcinoma. 2000 Dec 11 1
33 9888801 Inhibition of transcription elongation in the HER-2/neu coding sequence by triplex-directed covalent modification of the template strand. 1999 Jan 12 3
34 10487416 Correlation between the activation of Neu tyrosine kinase and promotion of foci formation induced by selected organochlorine compounds in the MCF-7 model system. 1999 2
35 9698539 Antisense oligonucleotides specific for the HER2/neu oncogene inhibit the growth of human breast carcinoma cells that overexpress HER2/neu. 1998 Jun 8
36 9762367 Detection of c-erbB-2 mRNAs using dig-labelled oligonucleotide probe with in situ hybridisation in human breast carcinoma: comparison with immunohistochemical results. 1998 1
37 8564964 Temporary ex vivo inhibition of the expression of the human oncogene HER2 (NEU) by a triple helix-forming oligonucleotide. 1996 Feb 1 1
38 8721099 [Basic studies on the 111In labeled antisense oligonucleotide for tumor imaging]. 1996 Feb 1
39 8783791 Inhibition of erbB-2-positive breast cancer cell growth by erbB-2 antisense oligonucleotides. 1996 Spring 4
40 8948649 Inhibition of the erbB-2 tyrosine kinase receptor in breast cancer cells by phosphoromonothioate and phosphorodithioate antisense oligonucleotides. 1996 Nov 15 1
41 7909438 Reduction of erbB2 gene product in mamma carcinoma cell lines by erbB2 mRNA-specific and tyrosine kinase consensus phosphorothioate antisense oligonucleotides. 1994 Apr 15 3
42 7914192 Binding of an ETS-related protein within the DNase I hypersensitive site of the HER2/neu promoter in human breast cancer cells. 1994 Aug 5 1
43 7947086 erbB-2 antisense oligonucleotides inhibit the proliferation of breast carcinoma cells with erbB-2 oncogene amplification. 1994 Nov 12
44 7901237 Triplex formation inhibits HER-2/neu transcription in vitro. 1993 Nov 3
45 1348216 Effects of beta-2 microglobulin anti-sense oligonucleotides on sensitivity of HER2/neu oncogene-expressing and nonexpressing target cells to lymphocyte-mediated lysis. 1992 Apr 15 1
46 1749520 Short biotinylated oligonucleotides bind non-specifically to senile plaques of Alzheimer's disease. 1991 Sep 2 1