Title : Temporary ex vivo inhibition of the expression of the human oncogene HER2 (NEU) by a triple helix-forming oligonucleotide.

Pub. Date : 1996 Feb 1

PMID : 8564964






1 Functional Relationships(s)
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1 At a concentration of 2 microM, the oligonucleotide reduced within 6 h the HER2 mRNA level to 42% (Northern blot) but did not interfere with the transcription of a housekeeping gene, glyceraldehyde-3-phosphate dehydrogenase. Oligonucleotides erb-b2 receptor tyrosine kinase 2 Homo sapiens