epigallocatechin gallate

erb-b2 receptor tyrosine kinase 2 ; Homo sapiens







24 Article(s)
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1 34940773 Multi-ligand modified PC@DOX-PA/EGCG micelles effectively inhibit the growth of ER+, PR+ or HER2+ breast cancer. 2022 Jan 19 1
2 31934166 ERα36 is an effective target of epigallocatechin-3-gallate in hepatocellular carcinoma. 2019 2
3 29329808 Structural and energetic basis for the molecular recognition of dual synthetic vs. natural inhibitors of EGFR/HER2. 2018 May 1
4 30207689 Cascaded Aptamers-Governed Multistage Drug-Delivery System Based on Biodegradable Envelope-Type Nanovehicle for Targeted Therapy of HER2-Overexpressing Breast Cancer. 2018 Oct 10 4
5 28462491 In vitro evaluation of combination of EGCG and Erlotinib with classical chemotherapeutics on JAR cells. 2017 Aug 1
6 26107737 Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs. 2015 1
7 20664987 In vitro mechanism of action for the cytotoxicity elicited by the combination of epigallocatechin gallate and raloxifene in MDA-MB-231 cells. 2010 Sep 1
8 19113837 (-)-Epigallocatechin-3-gallate is a novel Hsp90 inhibitor. 2009 Jan 20 1
9 19420761 Inhibitory effect of (-)-epigallocatechin and (-)-epigallocatechin gallate against heregulin beta1-induced migration/invasion of the MCF-7 breast carcinoma cell line. 2009 May 2
10 19438225 (-)-Epigallocatechin-3-gallate inhibits Hsp90 function by impairing Hsp90 association with cochaperones in pancreatic cancer cell line Mia Paca-2. 2009 Jul-Aug 1
11 17902053 Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75. 2008 Jun 1
12 18618485 Comparison of delphinidin, quercetin and (-)-epigallocatechin-3-gallate as inhibitors of the EGFR and the ErbB2 receptor phosphorylation. 2008 Jul 4
13 19189648 Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals. 2008 Nov-Dec 2
14 19325845 Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG. 2008 Jun 4
15 17539658 Tea polyphenol (-)-epigallocatechin 3-gallate suppresses heregulin-beta1-induced fatty acid synthase expression in human breast cancer cells by inhibiting phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase cascade signaling. 2007 Jun 27 1
16 17575143 Activation of FOXO3a by the green tea polyphenol epigallocatechin-3-gallate induces estrogen receptor alpha expression reversing invasive phenotype of breast cancer cells. 2007 Jun 15 2
17 17909003 Trastuzumab-resistant HER2-driven breast cancer cells are sensitive to epigallocatechin-3 gallate. 2007 Oct 1 5
18 16707458 Microarray-assisted pathway analysis identifies mitogen-activated protein kinase signaling as a mediator of resistance to the green tea polyphenol epigallocatechin 3-gallate in her-2/neu-overexpressing breast cancer cells. 2006 May 15 1
19 15814656 (-)-Epigallocatechin gallate and polyphenon E inhibit growth and activation of the epidermal growth factor receptor and human epidermal growth factor receptor-2 signaling pathways in human colon cancer cells. 2005 Apr 1 7
20 16053920 EGCG inhibits activation of the insulin-like growth factor-1 receptor in human colon cancer cells. 2005 Sep 2 1
21 16140980 Mechanism of action of (-)-epigallocatechin-3-gallate: auto-oxidation-dependent inactivation of epidermal growth factor receptor and direct effects on growth inhibition in human esophageal cancer KYSE 150 cells. 2005 Sep 1 1
22 16416603 EGCG inhibits activation of HER3 and expression of cyclooxygenase-2 in human colon cancer cells. 2005 3
23 12960141 Epigallocatechin-3-gallate inhibits activation of HER-2/neu and downstream signaling pathways in human head and neck and breast carcinoma cells. 2003 Aug 15 1
24 11830514 Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/neu signaling, proliferation, and transformed phenotype of breast cancer cells. 2002 Feb 1 7