Title : Platinum compounds in the treatment of advanced breast cancer.

Pub. Date : 2001 Oct

PMID : 11899413






6 Functional Relationships(s)
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1 Interest in platinum compounds for the treatment of breast cancer has been reawakened because of preclinical studies indicating synergy of platinum salts with the monoclonal antibody trastuzumab in human breast cancer cell lines that overexpress HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens
2 Interest in platinum compounds for the treatment of breast cancer has been reawakened because of preclinical studies indicating synergy of platinum salts with the monoclonal antibody trastuzumab in human breast cancer cell lines that overexpress HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens
3 Of greatest interest is the synergy between the platinum derivatives and the monoclonal antibody trastuzumab demonstrated in vitro in breast cancer cell lines overexpressing HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens
4 Of greatest interest is the synergy between the platinum derivatives and the monoclonal antibody trastuzumab demonstrated in vitro in breast cancer cell lines overexpressing HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens
5 Currently, several combinations of platinum compounds (either cisplatin or carboplatin) with docetaxel and trastuzumab are under clinical testing in patients with MBC who overexpress HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens
6 Currently, several combinations of platinum compounds (either cisplatin or carboplatin) with docetaxel and trastuzumab are under clinical testing in patients with MBC who overexpress HER2/neu. Platinum erb-b2 receptor tyrosine kinase 2 Homo sapiens