| 1 |
35527005 | Dexmedetomidine attenuates acute stress-induced liver injury in rats by regulating the miR-34a-5p/ROS/JNK/p38 signaling pathway. | 2022 |
1 |
| 2 |
33076786 | Dexmedetomidine improves postoperative neurocognitive disorder after cardiopulmonary bypass in rats. | 2021 Feb |
1 |
| 3 |
33220608 | Dexmedetomidine exerts cardioprotective effect through miR-146a-3p targeting IRAK1 and TRAF6 via inhibition of the NF-κB pathway. | 2021 Jan |
2 |
| 4 |
33499703 | Dexmedetomidine postconditioning alleviates spinal cord ischemia-reperfusion injury in rats via inhibiting neutrophil infiltration, microglia activation, reactive gliosis and CXCL13/CXCR5 axis activation. | 2021 Mar 11 |
1 |
| 5 |
33725228 | Dexmedetomidine reversed hypoxia/reoxygenation injury-induced oxidative stress and endoplasmic reticulum stress-dependent apoptosis of cardiomyocytes via SIRT1/CHOP signaling pathway. | 2021 Jul |
1 |
| 6 |
34121490 | Protective effect of dexmedetomidine on neuronal hypoxic injury through inhibition of miR-134. | 2021 Dec |
3 |
| 7 |
34135573 | High-Dose Dexmedetomidine Promotes Apoptosis in Fetal Rat Hippocampal Neurons. | 2021 |
2 |
| 8 |
34182937 | Dexmedetomidine post-conditioning attenuates cerebral ischemia following asphyxia cardiac arrest through down-regulation of apoptosis and neuroinflammation in rats. | 2021 Jun 28 |
1 |
| 9 |
34237977 | Dexmedetomidine attenuates cerebral ischemia-reperfusion injury in rats by inhibiting the JNK pathway. | 2021 Jun |
3 |
| 10 |
34363182 | Dexmedetomidine Alleviates Lipopolysaccharide-Induced Hippocampal Neuronal Apoptosis via Inhibiting the p38 MAPK/c-Myc/CLIC4 Signaling Pathway in Rats. | 2021 Nov |
1 |
| 11 |
31635678 | The Role of Janus Kinase/Signal Transducer and Activator of Transcription Signalling on Preventing Intestinal Ischemia/Reperfusion Injury with Dexmedetomidine. | 2020 May 1 |
1 |
| 12 |
32034118 | The Effects of Dexmedetomidine in a Rat Model of Sepsis-Induced Lung Injury are Mediated Through the Adenosine Monophosphate-Activated Protein Kinase (AMPK)/Silent Information Regulator 1 (SIRT1) Pathway. | 2020 Feb 8 |
1 |
| 13 |
32337274 | TRPV1 Contributes to the Neuroprotective Effect of Dexmedetomidine in Pilocarpine-Induced Status Epilepticus Juvenile Rats. | 2020 |
1 |
| 14 |
32419697 | Dexmedetomidine Attenuates Glutamate-Induced Cytotoxicity by Inhibiting the Mitochondrial-Mediated Apoptotic Pathway. | 2020 May 18 |
1 |
| 15 |
32538430 | Dexmedetomidine exerts neuroprotective effects during high glucose-induced neural injury by inhibiting miR-125b. | 2020 Jun 26 |
1 |
| 16 |
32655771 | Dexmedetomidine Ameliorates Lung Injury Induced by Intestinal Ischemia/Reperfusion by Upregulating Cannabinoid Receptor 2, Followed by the Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway. | 2020 |
1 |
| 17 |
32848754 | The Protective Effect and Mechanism of Dexmedetomidine on Diabetic Peripheral Neuropathy in Rats. | 2020 |
1 |
| 18 |
33000208 | Effects of local dexmedetomidine administration on the neurotoxicity of ropivacaine for sciatic nerve block in rats. | 2020 Nov |
3 |
| 19 |
33117159 | Dexmedetomidine Mediates Neuroglobin Up-Regulation and Alleviates the Hypoxia/Reoxygenation Injury by Inhibiting Neuronal Apoptosis in Developing Rats. | 2020 |
1 |
| 20 |
33173983 | Dexmedetomidine reduces ventilator-induced lung injury via ERK1/2 pathway activation. | 2020 Dec |
1 |
| 21 |
33275257 | Protective effect of dexmedetomidine against renal injury in diabetic nephropathy rats through inhibiting NF-κB pathway. | 2020 Nov |
1 |
| 22 |
30613136 | Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats. | 2019 |
1 |
| 23 |
30655009 | [Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats]. | 2019 Mar - Apr |
1 |
| 24 |
30657579 | Dexmedetomidine alleviates lung ischemia-reperfusion injury in rats by activating PI3K/Akt pathway. | 2019 Jan |
1 |
| 25 |
31220473 | Dexmedetomidine protects neurons from kainic acid-induced excitotoxicity by activating BDNF signaling. | 2019 Oct |
2 |
| 26 |
31308624 | Dexmedetomidine protects PC12 cells from lidocaine-induced cytotoxicity via downregulation of Stathmin 1. | 2019 |
1 |
| 27 |
31389589 | Effects of dexmedetomidine on sepsis-induced liver injury in rats. | 2019 Aug |
1 |
| 28 |
31511220 | [Protective effects of dexmedetomidine against pulmonary ischemia-reperfusion injury during cardiopulmonary bypass in rats]. | 2019 Aug 30 |
1 |
| 29 |
31682592 | Dexmedetomidine inhibits neuronal apoptosis by inducing Sigma-1 receptor signaling in cerebral ischemia-reperfusion injury. | 2019 Nov 4 |
1 |
| 30 |
31702043 | Dexmedetomidine protects against sepsis‑associated encephalopathy through Hsp90/AKT signaling. | 2019 Nov |
1 |
| 31 |
29864919 | Taurine enhances the protective effect of Dexmedetomidine on sepsis-induced acute lung injury via balancing the immunological system. | 2018 Jul |
1 |
| 32 |
30017939 | Comparison of neurotoxicity of dexmedetomidine as an adjuvant in brachial plexus block in rats of different age. | 2018 Sep - Oct |
2 |
| 33 |
27959438 | Dexmedetomidine attenuates lipopolysaccharide-induced acute lung injury by inhibiting oxidative stress, mitochondrial dysfunction and apoptosis in rats. | 2017 Jan |
2 |
| 34 |
28007581 | Different doses of dexmedetomidine reduce plasma cytokine production, brain oxidative injury, PARP and caspase expression levels but increase liver oxidative toxicity in cerebral ischemia-induced rats. | 2017 Apr |
2 |
| 35 |
28436683 | Dexmedetomidine Protects PC12 Cells from Lidocaine-Induced Cytotoxicity Through Downregulation of COL3A1 Mediated by miR-let-7b. | 2017 Jul |
1 |
| 36 |
28463790 | Dexmedetomidine inhibits activation of the MAPK pathway and protects PC12 and NG108-15 cells from lidocaine-induced cytotoxicity at its maximum safe dose. | 2017 Jul |
1 |
| 37 |
25844953 | Dexmedetomidine Attenuates Neurotoxicity Induced by Prenatal Propofol Exposure. | 2016 Jan |
1 |
| 38 |
27221008 | Effects of dexmedetomidine postconditioning on myocardial ischemia and the role of the PI3K/Akt-dependent signaling pathway in reperfusion injury. | 2016 Jul |
1 |
| 39 |
27872485 | The neuroprotective action of dexmedetomidine on apoptosis, calcium entry and oxidative stress in cerebral ischemia-induced rats: Contribution of TRPM2 and TRPV1 channels. | 2016 Nov 22 |
2 |
| 40 |
25916972 | Systemic physiology and neuroapoptotic profiles in young and adult rats exposed to surgery: A randomized controlled study comprising four different anaesthetic techniques. | 2015 Oct |
1 |
| 41 |
26622369 | Protective effects of dexmedetomidine on intestinal ischemia-reperfusion injury. | 2015 Aug |
1 |
| 42 |
26770320 | Dexmedetomidine attenuates isoflurane-induced cognitive impairment through antioxidant, anti-inflammatory and anti-apoptosis in aging rat. | 2015 |
1 |
| 43 |
22150679 | Dexmedetomidine protects against oxygen-glucose deprivation-induced injury through the I2 imidazoline receptor-PI3K/AKT pathway in rat C6 glioma cells. | 2012 Jan |
1 |
| 44 |
20003127 | Dexmedetomidine provides cortical neuroprotection: impact on anaesthetic-induced neuroapoptosis in the rat developing brain. | 2010 Jul |
1 |
| 45 |
19352168 | Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats. | 2009 May |
1 |
| 46 |
19691839 | Sedation improves early outcome in severely septic Sprague Dawley rats. | 2009 |
1 |
| 47 |
16249671 | Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions. | 2005 Nov |
3 |