Cisplatin

caspase 3 ; Rattus norvegicus







61 Article(s)
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1 33533291 Thymoquinone Potentiated the Anticancer Effect of Cisplatin on Hepatic Tumorigenesis by Modulating Tissue Oxidative Stress and Endoplasmic GRP78/CHOP Signaling. 2022 1
2 34877753 p-Coumaric acid alleviates cisplatin-induced ovarian toxicity in rats. 2022 Feb 1
3 35099041 Cisplatin-induced alterations in the blood-nerve barrier: effects of combination of vitamin B1, B6 and B12. 2022 Jan 31 1
4 35197751 Impact of preconditioning stem cells with all-trans retinoic acid signaling pathway on cisplatin-induced nephrotoxicity by down-regulation of TGFβ1, IL-6, and caspase-3 and up-regulation of HIF1α and VEGF. 2022 Feb 1
5 35357583 Protective effect of edaravone on cisplatin-induced injury in rat ovary. 2022 Mar 31 2
6 33650929 Protective effects of nobiletin on cisplatin induced neurotoxicity in rats. 2021 Mar 8 1
7 34268770 Evaluation of protective effects of gallic acid on cisplatin-induced testicular and epididymal damage. 2021 Nov 1
8 34318554 Betaine downregulates microRNA 34a expression via a p53-dependent manner in cisplatin-induced nephrotoxicity in rats. 2021 Sep 3
9 34787874 AMP-activated protein kinase contributes to ROS-mediated p53 activation in cisplatin-induced nephrotoxicity. 2021 Nov 1
10 34886721 Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats. 2021 Dec 9 1
11 34916822 Antioxidant and Anti-inflammatory Properties Mediate the Neuroprotective Effects of Hydro-ethanolic Extract of Tiliacora triandra Against Cisplatin-induced Neurotoxicity. 2021 1
12 33235694 The investigation of the effect of fraxin on hepatotoxicity induced by cisplatin in rats. 2020 Nov 1
13 31103702 Wogonin pre-treatment attenuates cisplatin-induced nephrotoxicity in rats: Impact on PPAR-γ, inflammation, apoptosis and Wnt/β-catenin pathway. 2019 Aug 1 1
14 31129703 Mechanistic perspective of protective effects of resveratrol against cisplatin-induced ovarian injury in rats: emphasis on anti-inflammatory and anti-apoptotic effects. 2019 Oct 1
15 31152701 Tetramethylpyrazine guards against cisplatin-induced nephrotoxicity in rats through inhibiting HMGB1/TLR4/NF-κB and activating Nrf2 and PPAR-γ signaling pathways. 2019 Aug 15 1
16 31197431 Piceatannol protects against cisplatin nephrotoxicity via activation of Nrf2/HO-1 pathway and hindering NF-κB inflammatory cascade. 2019 Nov 1
17 31401317 Molecular mechanisms of Cisplatin- induced placental toxicity and teratogenicity in rats and the ameliorating role of N-acetyl-cysteine. 2019 Oct 2
18 31590115 Inhibition of NF-κB and the oxidative stress -dependent caspase-3 apoptotic pathway by betaine supplementation attenuates hepatic injury mediated by cisplatin in rats. 2019 Dec 1
19 31803569 Effect of Suramin on Renal Proximal Tubular Cells Damage Induced by Cisplatin in Rats (Histological and Immunohistochemical Study). 2019 Oct-Dec 2
20 29216766 Vanillin mitigates the adverse impact of cisplatin and methotrexate on rat kidneys. 2018 Sep 1
21 29494988 The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats. 2018 Apr 1
22 29545862 Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats. 2018 Apr 2
23 29897076 Honey protects against cisplatin-induced hepatic and renal toxicity through inhibition of NF-κB-mediated COX-2 expression and the oxidative stress dependent BAX/Bcl-2/caspase-3 apoptotic pathway. 2018 Jul 17 1
24 30021657 The role of mesenchymal stem cells in chemotherapy-induced gonadotoxicity. 2018 Jul 18 1
25 30683829 Cysteinyl leukotrienes predominantly mediate cisplatin-induced acute renal damage in male rats. 2018 Oct 1
26 27823926 Cisplatin-induced neuropathic pain is mediated by upregulation of N-type voltage-gated calcium channels in dorsal root ganglion neurons. 2017 Feb 1
27 28282556 Mechanisms involved in the possible nephroprotective effect of rutin and low dose γ irradiation against cisplatin-induced nephropathy in rats. 2017 Apr 1
28 28413323 Preventive effect of fermented black ginseng against cisplatin-induced nephrotoxicity in rats. 2017 Apr 1
29 26691328 Knocking down Dp71 expression in A549 cells reduces its malignancy in vivo and in vitro. 2016 1
30 26775661 Emodin ameliorates cisplatin-induced apoptosis of rat renal tubular cells in vitro by activating autophagy. 2016 Feb 1
31 27417335 Indole-3-carbinol protects against cisplatin-induced acute nephrotoxicity: role of calcitonin gene-related peptide and insulin-like growth factor-1. 2016 Jul 15 1
32 27571604 Inhibition of PARP activation by enalapril is crucial for its renoprotective effect in cisplatin-induced nephrotoxicity in rats. 2016 1
33 28101235 Protective effect of selenium against cisplatin-induced nasopharyngeal cancer in male albino rats. 2016 Dec 1
34 25704027 Glutamine protects against cisplatin-induced nephrotoxicity by decreasing cisplatin accumulation. 2015 Jan 1
35 25719941 Protective effect of tetrahydrocurcumin against cisplatin-induced renal damage: in vitro and in vivo studies. 2015 Mar 1
36 26002685 Nobiletin ameliorates cisplatin-induced acute kidney injury due to its anti-oxidant, anti-inflammatory and anti-apoptotic effects. 2015 Jul-Aug 1
37 26536032 Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs. 2015 1
38 24054220 Renoprotective effects of Maillard reaction products generated during heat treatment of ginsenoside Re with leucine. 2014 Jan 15 1
39 24434421 Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1. 2014 Mar 2
40 24817286 Role of reactive oxygen species in p53 activation during cisplatin-induced apoptosis of rat mesangial cells. 2014 1
41 23353054 Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage. 2013 Mar 15 1
42 23618405 Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro. 2013 Apr 25 1
43 21044617 Carvedilol protects against cisplatin-induced oxidative stress, redox state unbalance and apoptosis in rat kidney mitochondria. 2011 Jan 15 1
44 21602180 Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity. 2011 Nov 1
45 21605616 Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α and caspase-3 expression in wistar rats. 2011 Sep 1
46 21795690 Role of extracellular matrix renal tubulo-interstitial nephritis antigen (TINag) in cell survival utilizing integrin (alpha)vbeta3/focal adhesion kinase (FAK)/phosphatidylinositol 3-kinase (PI3K)/protein kinase B-serine/threonine kinase (AKT) signaling pathway. 2011 Sep 30 1
47 19883181 Endogenous protection against oxidative stress caused by cisplatin: role of superoxide dismutase. 2010 Apr 1
48 20883750 Epicatechin protects the auditory organ by attenuating cisplatin-induced ototoxicity through inhibition of ERK. 2010 Dec 15 1
49 19254279 Anti-apoptotic effects of protein kinase C-delta and c-fos in cisplatin-treated thyroid cells. 2009 Mar 2
50 19713707 Alpha-lipoic acid attenuates cisplatin-induced tubulointerstitial injuries through inhibition of mitochondrial bax translocation in rats. 2009 1