Lanosterol

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







13 Article(s)
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1 31902650 Luciferase-based HMG-CoA reductase degradation assay for activity and selectivity profiling of oxy(lano)sterols. 2020 Feb 1 1
2 32616181 Bisphosphonate esters interact with HMG-CoA reductase membrane domain to induce its degradation. 2020 Jul 15 2
3 32877255 The Polymorphism rs2968 of LSS Gene Confers Susceptibility to Age-Related Cataract. 2020 Nov 1
4 31455613 Endogenous sterol intermediates of the mevalonate pathway regulate HMGCR degradation and SREBP-2 processing. 2019 Oct 3
5 18024962 Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. 2008 Jan 18 1
6 17393208 Syntheses of ring C oxysterols: inhibitors of sterol biosynthesis. 2007 Feb 1
7 17635920 Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs. 2007 Sep 14 1
8 16054061 Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. 2005 Mar 1
9 7840615 15-substituted lanosterols: post-transcriptional suppressors of 3-hydroxy-3-methylglutaryl coenzyme A reductase. 1995 Jan 10 1
10 1464112 Effects of 32-oxygenated lanosterol derivatives on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and cholesterol biosynthesis from 24,25-dihydrolanosterol. 1992 Oct 2
11 2293333 Determination of serum levels of unesterified lanosterol by isotope dilution-mass spectrometry. 1990 Nov 3
12 3624256 In situ accumulation of 3 beta-hydroxylanost-8-en-32-aldehyde in hepatocyte cultures. A putative regulator of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity. 1987 Sep 5 2
13 4052443 Inhibition, post-hydroxymethylglutaryl-CoA regulation and relation to cell growth of cholesterol biosynthesis in cultured human skin fibroblasts. 1985 Nov 14 1