Rosuvastatin Calcium

3-hydroxy-3-methylglutaryl-CoA reductase ; Homo sapiens







47 Article(s)
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1 33428168 Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults. 2021 Feb 1
2 30290001 Unfolding the pleiotropic facades of rosuvastatin in therapeutic intervention of myriads of neurodegenerative disorders. 2019 Apr 1
3 30942448 Potentiation of mitotane action by rosuvastatin: New insights for adrenocortical carcinoma management. 2019 Jun 2
4 29533074 Analytical Methods for the Determination of Rosuvastatin in Pharmaceutical Formulations and Biological Fluids: A Critical Review. 2018 Jul 4 2
5 29692602 Pharmacokinetic interactions and tolerability of rosuvastatin and ezetimibe: an open-label, randomized, multiple-dose, crossover study in healthy male volunteers. 2018 1
6 27941393 Use of rosuvastatin in HIV-associated chronic obstructive pulmonary disease. 2017 Feb 20 1
7 25719441 Effect of Omeprazole on the Pharmacokinetics of Rosuvastatin in Healthy Male Volunteers. 2016 Nov/Dec 1
8 26908399 Varicose Remodeling of Veins Is Suppressed by 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors. 2016 Feb 23 1
9 26930419 Rosuvastatin: Beyond the cholesterol-lowering effect. 2016 May 1
10 25453767 HMG-CoA reductase inhibitor rosuvastatin improves abnormal brain electrical activity via mechanisms involving eNOS. 2015 Jan 22 2
11 25767372 A pharmacokinetic and pharmacodynamic drug interaction between rosuvastatin and valsartan in healthy subjects. 2015 1
12 26081159 Marked Alteration of Rosuvastatin Pharmacokinetics in Healthy Chinese with ABCG2 34G>A and 421C>A Homozygote or Compound Heterozygote. 2015 Sep 1
13 26093357 Identification of transformation products of rosuvastatin in water during ZnO photocatalytic degradation through the use of associated LC-QTOF-MS to computational chemistry. 2015 Dec 15 2
14 26411232 Transient azoospermia following rosuvastatin medication for hypercholesterolemia. 2015 2
15 25128668 Statins in therapy: understanding their hydrophilicity, lipophilicity, binding to 3-hydroxy-3-methylglutaryl-CoA reductase, ability to cross the blood brain barrier and metabolic stability based on electrostatic molecular orbital studies. 2014 Oct 6 2
16 23256625 Evaluation of drug interactions of GSK1292263 (a GPR119 agonist) with statins: from in vitro data to clinical study design. 2013 Jun 1
17 23447089 Effect of food on the pharmacokinetics of rosuvastatin after administration of a single oral dose in dogs. 2013 Mar 1
18 24137286 Rosuvastatin suppresses platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferation and migration via the MAPK signaling pathway. 2013 Oct 1
19 22442638 Rosuvastatin: a review of the pharmacology and clinical effectiveness in cardiovascular disease. 2012 1
20 21881526 Angiotensin-II and rosuvastatin influence matrix remodeling in human mesangial cells via metalloproteinase modulation. 2011 Oct 1
21 19956889 Vascular damage in testicular cancer patients: a study on endothelial activation by bleomycin and cisplatin in vitro. 2010 Jan 1
22 20653359 Effects of lipid-lowering therapy on reduction of cardiovascular events in patients with end-stage renal disease requiring hemodialysis. 2010 Aug 1
23 21701608 Long-term use of rosuvastatin: a critical risk benefit appraisal and comparison with other antihyperlipidemics. 2009 1
24 17692320 The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. 2008 Feb 1
25 18177480 In vitro anti-oxidant and DNA protective effects of the novel 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor rosuvastatin. 2008 May 1
26 18355422 The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics. 2008 Apr 1
27 17577102 Rosuvastatin suppresses the inflammatory responses through inhibition of c-Jun N-terminal kinase and Nuclear Factor-kappaB in endothelial cells. 2007 Jun 1
28 16581327 Statin safety: an appraisal from the adverse event reporting system. 2006 Apr 17 1
29 16128507 Rosuvastatin: a high-potency HMG-CoA reductase inhibitor. 2005 Jul-Aug 1
30 16144509 Rosuvastatin: a risk-benefit assessment for intensive lipid lowering. 2005 Sep 1
31 15137986 Quantification of the N-desmethyl metabolite of rosuvastatin in human plasma by automated SPE followed by HPLC with tandem MS detection. 2004 May 28 1
32 12534645 Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects. 2003 Jan 1
33 12682802 The effect of erythromycin on the pharmacokinetics of rosuvastatin. 2003 May 1
34 12709722 Effect of itraconazole on the pharmacokinetics of rosuvastatin. 2003 Apr 1
35 12773150 Molecular mechanism for inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase by rosuvastatin. 2003 Jun 1
36 12824720 Rosuvastatin--a highly effective new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor: review of clinical trial data at 10-40 mg doses in dyslipidemic patients. 2003 1
37 14512129 A double-blind, randomized, incomplete crossover trial to assess the dose proportionality of rosuvastatin in healthy volunteers. 2003 Aug 1
38 14667956 Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers. 2003 Oct 1
39 14693307 Metabolism, excretion, and pharmacokinetics of rosuvastatin in healthy adult male volunteers. 2003 Nov 1
40 14983742 [Dyslipidemia and global cardiovascular risk: treatment guidelines]. 2003 Dec 1
41 14983747 [Ongoing trials and future prospects]. 2003 Dec 1
42 15030249 Rosuvastatin: a new inhibitor of HMG-coA reductase for the treatment of dyslipidemia. 2003 Nov 2
43 11772327 Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. 2002 Jan 1
44 12269853 Rosuvastatin. 2002 1
45 12445025 Pharmacodynamic effects and pharmacokinetics of a new HMG-CoA reductase inhibitor, rosuvastatin, after morning or evening administration in healthy volunteers. 2002 Nov 1
46 12481202 Rosuvastatin: a highly effective new HMG-CoA reductase inhibitor. 2002 Winter 2
47 12769127 Rosuvastatin: a highly efficacious statin for the treatment of dyslipidaemia. 2002 Mar 1