| 1 |
28613690 | Statin Medications | 2022 Jan |
1 |
| 2 |
34911669 | Porcine reproductive and respiratory syndrome virus nsp4 positively regulates cellular cholesterol to inhibit type I interferon production. | 2022 Feb |
5 |
| 3 |
35101444 | Mitochondrial respiratory chain dysfunction alters ER sterol sensing and mevalonate pathway activity. | 2022 Mar |
1 |
| 4 |
35213538 | Characterising metabolomic signatures of lipid-modifying therapies through drug target mendelian randomisation. | 2022 Feb |
2 |
| 5 |
35221836 | Potential dual inhibitors of PCSK-9 and HMG-R from natural sources in cardiovascular risk management. | 2022 |
2 |
| 6 |
35321818 | Molecular targets of statins and their potential side effects: Not all the glitter is gold. | 2022 May 5 |
2 |
| 7 |
35359411 | Transcriptomics Reveals the Mevalonate and Cholesterol Pathways Blocking as Part of the Bacterial Cyclodipeptides Cytotoxic Effects in HeLa Cells of Human Cervix Adenocarcinoma. | 2022 |
1 |
| 8 |
35369058 | Aberrant Cholesterol Metabolic Genes Regulation in a Negative Feedback Loop Induced by an Alphacoronavirus. | 2022 |
1 |
| 9 |
35397399 | Synthesis of heterocyclic ring-fused analogs of HMG499 as novel degraders of HMG-CoA reductase that lower cholesterol. | 2022 Jun 5 |
3 |
| 10 |
35470784 | Effect of pH on structural dynamics of HMG-CoA reductase and binding affinity to β-sitosterol. | 2022 Apr 26 |
4 |
| 11 |
35533891 | Effects of statins on specialized pro-resolving mediators: An additional pathway leading to resolution of inflammation. | 2022 Jul |
1 |
| 12 |
35624221 | Polyploid giant cancer cells are dependent on cholesterol for progeny formation through amitotic division. | 2022 May 27 |
1 |
| 13 |
32860619 | Dietary Cholesterol Exacerbates Statin-Induced Hepatic Toxicity in Syrian Golden Hamsters and in Patients in an Observational Cohort Study. | 2021 Apr |
1 |
| 14 |
33167740 | Association of NPC1L1 and HMGCR Gene Polymorphisms with Major Adverse Cardiac and Cerebrovascular Events in Patients with Three-Vessel Disease. | 2021 Jun |
2 |
| 15 |
33307558 | Role of the Mevalonate Pathway in Adrenocortical Tumorigenesis. | 2021 Feb |
2 |
| 16 |
33412161 | A-family anti-inflammatory cyclopentenone prostaglandins: A novel class of non-statin inhibitors of HMG-CoA reductase. | 2021 Mar |
2 |
| 17 |
33414447 | MIEF2 reprograms lipid metabolism to drive progression of ovarian cancer through ROS/AKT/mTOR signaling pathway. | 2021 Jan 5 |
2 |
| 18 |
33422461 | Endothelial cells control vascular smooth muscle cell cholesterol levels by regulating 24-dehydrocholesterol reductase expression. | 2021 Feb 15 |
1 |
| 19 |
33428168 | Pharmacokinetics of Rosuvastatin: A Systematic Review of Randomised Controlled Trials in Healthy Adults. | 2021 Feb |
1 |
| 20 |
33550071 | Anti-hyperlipidemic potential of natural product based labdane-pyrroles via inhibition of cholesterol and triglycerides synthesis. | 2021 Mar |
1 |
| 21 |
33788186 | Anti-inflammatory Effects of Statins in Lung Vascular Pathology: From Basic Science to Clinical Trials. | 2021 |
1 |
| 22 |
33790100 | New Inhibitory Effect of Latilactobacillus sakei UONUMA on the Cholesterol Biosynthesis Pathway in Human HepG2 Cells. | 2021 |
1 |
| 23 |
33886544 | Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study. | 2021 Apr |
2 |
| 24 |
33965043 | Cholesterol was identified as a biomarker in human melanocytic nevi using DESI and DESI/PI mass spectrometry imaging. | 2021 Aug 15 |
2 |
| 25 |
33992804 | Targeting cholesterol biosynthesis promotes anti-tumor immunity by inhibiting long noncoding RNA SNHG29-mediated YAP activation. | 2021 Oct 6 |
2 |
| 26 |
34023025 | Phosphate meeting cholesterol-consequences for cardiovascular disease in chronic kidney disease? | 2021 Jun |
1 |
| 27 |
34041015 | Synergistic Effect of Statins and Abiraterone Acetate on the Growth Inhibition of Neuroblastoma via Targeting Androgen Receptor. | 2021 |
1 |
| 28 |
34219515 | Statin-Induced Autoimmune Necrotizing Myopathy. | 2021 Jan-Dec |
2 |
| 29 |
34222418 | Anti-tumor effect of statin on pancreatic adenocarcinoma: From concept to precision medicine. | 2021 Jun 26 |
2 |
| 30 |
34258925 | RNA-binding protein hnRNPR reduces neuronal cholesterol levels by binding to and suppressing HMGCR. | 2021 Jun 30 |
2 |
| 31 |
34303383 | Statins: a repurposed drug to fight cancer. | 2021 Jul 24 |
2 |
| 32 |
34313419 | Characterization of Citrus Pectin Oligosaccharides and Their Microbial Metabolites as Modulators of Immunometabolism on Macrophages. | 2021 Aug 4 |
2 |
| 33 |
34347016 | TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination. | 2021 Sep 6 |
1 |
| 34 |
34355128 | Anti-HMGCR antibodies and asymptomatic hyperCKemia. A case report. | 2021 Jun |
2 |
| 35 |
34369301 | Statins significantly repress rotavirus replication through downregulation of cholesterol synthesis. | 2021 Jan-Dec |
1 |
| 36 |
34425254 | Salsalate reduces atherosclerosis through AMPKβ1 in mice. | 2021 Nov |
1 |
| 37 |
34436503 | 2-Hydroxypropyl-β-cyclodextrin Regulates the Epithelial to Mesenchymal Transition in Breast Cancer Cells by Modulating Cholesterol Homeostasis and Endoplasmic Reticulum Stress. | 2021 Aug 23 |
2 |
| 38 |
34440098 | Enzymes in the Cholesterol Synthesis Pathway: Interactomics in the Cancer Context. | 2021 Jul 26 |
1 |
| 39 |
34449167 | Statin Associated Muscle Adverse Effects: From Presentation to Management. | 2021 Jun |
1 |
| 40 |
34621019 | CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer. | 2021 Dec |
2 |
| 41 |
34692687 | HMG-Coenzyme A Reductase as a Drug Target for the Prevention of Ankylosing Spondylitis. | 2021 |
3 |
| 42 |
34799335 | SNP of HMGCR and Apo E genes and their impact in response to statin therapy in hypercholesterolemic and hypertriglyceridemic patients in Pakistan. | 2021 Jul |
1 |
| 43 |
34804919 | TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer. | 2021 |
1 |
| 44 |
34830081 | A Possible Role for HMG-CoA Reductase Inhibitors and Its Association with HMGCR Genetic Variation in Parkinson's Disease. | 2021 Nov 11 |
3 |
| 45 |
34834649 | Aster glehni F. Schmidt Extract Modulates the Activities of HMG-CoA Reductase and Fatty Acid Synthase. | 2021 Oct 25 |
1 |
| 46 |
34842525 | Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1. | 2021 Nov 29 |
1 |
| 47 |
34866576 | Association of lipid-lowering drugs with COVID-19 outcomes from a Mendelian randomization study. | 2021 Dec 6 |
1 |
| 48 |
34908877 | Low Density Lipoprotein Receptor (LDLR) and 3-Hydroxy-3-Methylglutaryl Coenzyme a Reductase (HMGCR) Expression are Associated with Platinum-Resistance and Prognosis in Ovarian Carcinoma Patients. | 2021 |
4 |
| 49 |
34981026 | Rebaudioside A Enhances LDL Cholesterol Uptake in HepG2 Cells via Suppression of HMGCR Expression. | 2021 Oct |
1 |
| 50 |
34994160 | Differential associations of statin treatment and polymorphism in genes coding for HMGCR and PCSK9 to risk for insomnia. | 2021 Dec 30 |
1 |