Title : Berberine attenuates atherosclerotic lesions and hepatic steatosis in ApoE-/- mice by down-regulating PCSK9 via ERK1/2 pathway.

Pub. Date : 2021 Oct

PMID : 34790723






1 Functional Relationships(s)
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1 Finally, in vitro study showed that BBR promoted intracellular cholesterol efflux, up-regulated LDLR and down-regulated PCSK9 expression via the ERK1/2 pathway in cultured HepG2 cells. Berberine low density lipoprotein receptor Homo sapiens