| 1 |
35197312 | CYP2C19 plays a major role in the hepatic N-oxidation of cotinine. | 2022 Feb 23 |
2 |
| 2 |
30815984 | Evaluation of a weighted genetic risk score for the prediction of biomarkers of CYP2A6 activity. | 2020 Jan |
1 |
| 3 |
33375250 | Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation. | 2020 Dec 26 |
1 |
| 4 |
30611298 | Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci. | 2019 Jan 5 |
1 |
| 5 |
29158210 | Longitudinal Influence of Pregnancy on Nicotine Metabolic Pathways. | 2018 Feb |
1 |
| 6 |
27815364 | Predictors of Variation in CYP2A6 mRNA, Protein, and Enzyme Activity in a Human Liver Bank: Influence of Genetic and Nongenetic Factors. | 2017 Jan |
1 |
| 7 |
28542511 | Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study. | 2017 |
1 |
| 8 |
26818358 | Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity. | 2016 Mar |
1 |
| 9 |
27488534 | Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. | 2016 Oct 1 |
1 |
| 10 |
26014804 | Nicotine metabolite ratio (3-hydroxycotinine/cotinine) in plasma and urine by different analytical methods and laboratories: implications for clinical implementation. | 2015 Aug |
2 |
| 11 |
26132489 | Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. | 2015 |
1 |
| 12 |
24163286 | Influence of CYP2A6*4 genotypes on maternal serum cotinine among Chinese nonsmoking pregnant women. | 2014 Apr |
13 |
| 13 |
24859605 | Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. | 2014 Oct |
1 |
| 14 |
25220663 | Smilax China root extract detoxifies nicotine by reducing reactive oxygen species and inducing CYP2A6. | 2014 Oct |
1 |
| 15 |
23027621 | Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation. | 2013 Jan |
1 |
| 16 |
23211429 | Effects upon in-vivo nicotine metabolism reveal functional variation in FMO3 associated with cigarette consumption. | 2013 Feb |
2 |
| 17 |
23371292 | The ability of plasma cotinine to predict nicotine and carcinogen exposure is altered by differences in CYP2A6: the influence of genetics, race, and sex. | 2013 Apr |
11 |
| 18 |
23530019 | Nicotine kinetics in zebra finches in vivo and in vitro. | 2013 Jun |
1 |
| 19 |
23674838 | Stability of the nicotine metabolite ratio in smokers of progressively reduced nicotine content cigarettes. | 2013 Nov |
1 |
| 20 |
23714690 | CYP2A6 genotype but not age determines cotinine half-life in infants and children. | 2013 Sep |
2 |
| 21 |
23936477 | Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake. | 2013 |
3 |
| 22 |
22218454 | Substituted heteroaromatic compounds: effect on nicotine self-administration in rats. | 2012 Jun |
1 |
| 23 |
22382327 | Functional characterization of allelic variants of polymorphic human cytochrome P450 2A6 (CYP2A6*5, *7, *8, *18, *19, and *35). | 2012 |
2 |
| 24 |
22498344 | An LC-MS/MS method for concurrent determination of nicotine metabolites and the role of CYP2A6 in nicotine metabolite-mediated oxidative stress in SVGA astrocytes. | 2012 Sep 1 |
2 |
| 25 |
22552800 | Reproducibility of the nicotine metabolite ratio in cigarette smokers. | 2012 Jul |
1 |
| 26 |
22569203 | CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. | 2012 Jun |
1 |
| 27 |
22938167 | Nicotine intake and smoking topography in smokers with bipolar disorder. | 2012 Sep |
2 |
| 28 |
21597399 | The contribution of common CYP2A6 alleles to variation in nicotine metabolism among European-Americans. | 2011 Jul |
3 |
| 29 |
21919071 | Urinary biomarkers for secondhand smoke. | 2011 |
2 |
| 30 |
21964962 | Interaction between heavy smoking and CYP2A6 genotypes on type 2 diabetes and its possible pathways. | 2011 Dec |
1 |
| 31 |
20438369 | Association between nicotine metabolism and CYP2A6*1 and CYP2A6*4 genotypes in an Iranian population. | 2010 Jul |
4 |
| 32 |
20719908 | Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness. | 2010 Oct |
1 |
| 33 |
18216723 | A novel CYP2A6 allele, CYP2A6*23, impairs enzyme function in vitro and in vivo and decreases smoking in a population of Black-African descent. | 2008 Jan |
4 |
| 34 |
18360915 | Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent. | 2008 May |
4 |
| 35 |
18559554 | Stability of the nicotine metabolite ratio in ad libitum and reducing smokers. | 2008 Jun |
1 |
| 36 |
18779312 | Key residues controlling phenacetin metabolism by human cytochrome P450 2A enzymes. | 2008 Dec |
1 |
| 37 |
19029401 | Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer. | 2008 Dec |
1 |
| 38 |
17178771 | CYP2A13 metabolizes the substrates of human CYP1A2, phenacetin, and theophylline. | 2007 Mar |
1 |
| 39 |
17237153 | Inhibitory effects of neurotransmitters and steroids on human CYP2A6. | 2007 Apr |
2 |
| 40 |
17267622 | A novel duplication type of CYP2A6 gene in African-American population. | 2007 Apr |
2 |
| 41 |
17454704 | Sex-based and hormonal contraception effects on the metabolism of nicotine among adolescent tobacco-dependent smokers. | 2007 Apr |
1 |
| 42 |
17979512 | Genetic variability in CYP2A6 and the pharmacokinetics of nicotine. | 2007 Oct |
1 |
| 43 |
18041664 | Smoking behavior and related cancers: the role of CYP2A6 polymorphisms. | 2007 Dec |
1 |
| 44 |
16402086 | CYP2A6 polymorphisms are associated with nicotine dependence and influence withdrawal symptoms in smoking cessation. | 2006 Mar-Apr |
1 |
| 45 |
16402128 | Impact of CYP2A6 genotype on pretreatment smoking behaviour and nicotine levels from and usage of nicotine replacement therapy. | 2006 Apr |
1 |
| 46 |
16636685 | CYP2A7 polymorphic alleles confound the genotyping of CYP2A6*4A allele. | 2006 Nov-Dec |
1 |
| 47 |
16765148 | Nicotine metabolite ratio predicts efficacy of transdermal nicotine for smoking cessation. | 2006 Jun |
1 |
| 48 |
16952495 | Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations. | 2006 Sep |
1 |
| 49 |
17035386 | CYP2A6 genotype, phenotype, and the use of nicotine metabolites as biomarkers during ad libitum smoking. | 2006 Oct |
8 |
| 50 |
17112802 | CYP2A6 genotype and the metabolism and disposition kinetics of nicotine. | 2006 Nov |
1 |