| 1 |
33589424 | Therapeutically Increasing MHC-I Expression Potentiates Immune Checkpoint Blockade. | 2021 Jun |
1 |
| 2 |
34050412 | Effects of Birinapant on Proliferation and Invasion of MGC-803 Gastric Cancer Cells and Mechanism Underlying These Effects. | 2021 May |
1 |
| 3 |
32341449 | Targeting triple-negative breast cancers with the Smac-mimetic birinapant. | 2020 Oct |
1 |
| 4 |
33097020 | Pharmacodynamic modeling of synergistic birinapant/paclitaxel interactions in pancreatic cancer cells. | 2020 Oct 23 |
2 |
| 5 |
33108350 | Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis. | 2020 Dec 3 |
1 |
| 6 |
33334024 | Matrix Drug Screen Identifies Synergistic Drug Combinations to Augment SMAC Mimetic Activity in Ovarian Cancer. | 2020 Dec 15 |
1 |
| 7 |
29467909 | Apoptosis-sensitizing activity of birinapant in head and neck squamous cell carcinoma cell lines. | 2018 Mar |
2 |
| 8 |
30344003 | SMAC Mimetics Induce Autophagy-Dependent Apoptosis of HIV-1-Infected Resting Memory CD4+ T Cells. | 2018 Nov 14 |
2 |
| 9 |
28460471 | NCTD promotes Birinapant-mediated anticancer activity in breast cancer cells by downregulation of c-FLIP. | 2017 Apr 18 |
1 |
| 10 |
26446940 | Effect of a Smac Mimetic (TL32711, Birinapant) on the Apoptotic Program and Apoptosis Biomarkers Examined with Validated Multiplex Immunoassays Fit for Clinical Use. | 2016 Feb 15 |
4 |
| 11 |
26566079 | Pharmacodynamic markers and clinical results from the phase 2 study of the SMAC mimetic birinapant in women with relapsed platinum-resistant or -refractory epithelial ovarian cancer. | 2016 Feb 15 |
1 |
| 12 |
26859455 | Targeting p38 or MK2 Enhances the Anti-Leukemic Activity of Smac-Mimetics. | 2016 Feb 8 |
1 |
| 13 |
26944210 | Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells. | 2016 May 28 |
1 |
| 14 |
26985322 | Electrophilic Oxidation and [1,2]-Rearrangement of the Biindole Core of Birinapant. | 2016 Mar 10 |
4 |
| 15 |
27194727 | The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia. | 2016 May 18 |
4 |
| 16 |
27302164 | Acute Sensitivity of Ph-like Acute Lymphoblastic Leukemia to the SMAC-Mimetic Birinapant. | 2016 Aug 1 |
3 |
| 17 |
27469115 | SMAC Mimetic Birinapant plus Radiation Eradicates Human Head and Neck Cancers with Genomic Amplifications of Cell Death Genes FADD and BIRC2. | 2016 Sep 15 |
3 |
| 18 |
25902530 | Eliminating hepatitis B by antagonizing cellular inhibitors of apoptosis. | 2015 May 5 |
1 |
| 19 |
26095377 | Smac-derived Aza-peptide As an Aminopeptidase-resistant XIAP BIR3 Antagonist. | 2015 Jun 21 |
1 |
| 20 |
26333381 | A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma. | 2015 Nov |
2 |
| 21 |
26567362 | Promises and Challenges of Smac Mimetics as Cancer Therapeutics. | 2015 Nov 15 |
2 |
| 22 |
24526787 | Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents. | 2014 Feb |
1 |
| 23 |
24563541 | Birinapant (TL32711), a bivalent SMAC mimetic, targets TRAF2-associated cIAPs, abrogates TNF-induced NF-κB activation, and is active in patient-derived xenograft models. | 2014 Apr |
4 |
| 24 |
24684347 | Birinapant, a smac-mimetic with improved tolerability for the treatment of solid tumors and hematological malignancies. | 2014 May 8 |
1 |
| 25 |
23225169 | Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism. | 2013 Jan |
2 |
| 26 |
23403634 | The novel SMAC mimetic birinapant exhibits potent activity against human melanoma cells. | 2013 Apr 1 |
1 |