2-(4-morpholinoanilino)-6-cyclohexylaminopurine

TTK protein kinase ; Homo sapiens







9 Article(s)
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Title
Pub. Year
#Total Relationships
1 33505802 Reversine, a selective MPS1 inhibitor, induced autophagic cell death via diminished glucose uptake and ATP production in cholangiocarcinoma cells. 2021 2
2 34306198 Reversine inhibits proliferation, invasion and migration and induces cell apoptosis in gastric cancer cells by downregulating TTK. 2021 Sep 1
3 33584305 Dual Inhibition of γ-Tubulin and Plk1 Induces Mitotic Cell Death. 2020 1
4 29925769 Insights into Resistance Mechanisms of Inhibitors to Mps1 C604Y Mutation via a Comprehensive Molecular Modeling Study. 2018 Jun 20 2
5 28415765 Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines. 2017 Jun 13 1
6 28726638 Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures. 2017 Sep 1 1
7 27699881 Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase. 2016 Dec 3
8 22592527 Preferential killing of p53-deficient cancer cells by reversine. 2012 Jun 1 3
9 20624901 Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine. 2010 Jul 12 1