Title : Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.

Pub. Date : 2017 Jun 13

PMID : 28415765






1 Functional Relationships(s)
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1 Finally, we confirm that the reference compound reversine is a TTK inhibitor and like NTRC 0066-0, inhibits the proliferation of patient-derived colorectal cancer organoids. 2-(4-morpholinoanilino)-6-cyclohexylaminopurine TTK protein kinase Homo sapiens