Protein Name cytochrome P450, family 3, subfamily a, polypeptide 2
Organism Rattus norvegicus
Gene ID 266682
Gene Symbol

Cyp3a2

UniProt P05183 (CP3A2_RAT)
Relationships Total Number of functionally related compound(s) : 255
Total Number of Articles : 254
Description

cytochrome P450, family 3, subfamily a, polypeptide 2

Gene Summary

Enables demethylase activity and testosterone 6-beta-hydroxylase activity. Involved in oxidative demethylation and xenobiotic metabolic process. Predicted to be located in cytoplasm. Used to study anxiety disorder. Biomarker of cholestasis and end stage renal disease. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; and essential hypertension. Orthologous to human CYP3A5 (cytochrome P450 family 3 subfamily A member 5). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 3A2
  • CYPIIIA2
  • P450-PCN2
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Properties