cytochrome P450, family 3, subfamily a, polypeptide 2 ; Rattus norvegicus






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1 1417000 Effect of dexamethasone and phenobarbital on run-on transcription rate and CYP3A mRNA concentration in rat liver: changes during development. Arch Biochem Biophys 1992 Nov 1 3
2 1534660 Evaluation of loratadine as an inducer of liver microsomal cytochrome P450 in rats and mice. Biochem Pharmacol 1992 May 28 2
3 1715015 Selective induction of cytochrome P450e by kepone (chlordecone) in primary cultures of adult rat hepatocytes. Mol Pharmacol 1991 Aug 1
4 1731631 Cloning and characterization of a novel CYP3A1 allelic variant: analysis of CYP3A1 and CYP3A2 sex-hormone-dependent expression reveals that the CYP3A2 gene is regulated by testosterone. Arch Biochem Biophys 1992 Feb 14 1
5 2067545 Differential stability of drug-metabolizing enzyme activities in primary rat hepatocytes, cultured in the absence or presence of dexamethasone. Mutat Res 1991 Jul 2
6 2233686 Differentiated induction of cytochrome P450b/e and P450p mRNAs by dose of phenobarbital in primary cultures of adult rat hepatocytes. Mol Pharmacol 1990 Oct 5
7 2393297 Divergent effects of cycloheximide on the induction of class II and class III cytochrome P450 mRNAs in cultures of adult rat hepatocytes. Arch Biochem Biophys 1990 Sep 2
8 2628419 Role of growth hormone in modulating the constitutive and phenobarbital-induced levels of two P-450(6)beta (testosterone 6 beta-hydroxylase) mRNAs in rat livers. J Biochem 1989 Dec 1
9 3266213 A sex-specific form of cytochrome P-450 catalyzing propoxycoumarin O-depropylation and its identity with testosterone 6 beta-hydroxylase in untreated rat livers: reconstitution of the activity with microsomal lipids. J Biochem 1988 Nov 1
10 3785219 Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation. Mol Cell Biol 1986 Aug 4
11 7598745 Hormonal perturbation as a possible mechanism for the alteration of cytochrome P450 by cyclophosphamide. Biochem Pharmacol 1995 Jun 16 1
12 7726576 Transcriptional elements directing a liver-specific expression of P450/6 beta A (CYP3A2) gene-encoding testosterone 6 beta-hydroxylase. Arch Biochem Biophys 1995 Apr 1 1
13 7728897 Characterization of hepatic microsomal cytochrome P-450 from rats treated with methylsulphonyl metabolites of polychlorinated biphenyl congeners. Chem Biol Interact 1995 Apr 14 2
14 7736342 Effect of dexamethasone treatment on the biotransformation of glyceryl trinitrate: cytochrome P450 3A1 mediated activation of rat aortic guanylyl cyclase by glyceryl trinitrate. Can J Physiol Pharmacol 1994 Dec 2
15 7895610 In vitro metabolism of dorzolamide, a novel potent carbonic anhydrase inhibitor, in rat liver microsomes. Drug Metab Dispos 1994 Nov-Dec 1
16 7918645 Selective suppression of cytochrome P-450 gene expression by interleukins 1 and 6 in rat liver. Biochim Biophys Acta 1994 Oct 18 1
17 7979376 Structure of a gene and cDNA of a major constitutive form of testosterone 6 beta-hydroxylase (P450/6 beta A) encoding CYP3A2: comparison of the cDNA with P450PCN2. Arch Biochem Biophys 1994 Nov 1 1
18 8097709 Effects of clarithromycin and its metabolites on the mixed function oxidase system in hepatic microsomes of rats. Drug Metab Dispos 1993 Mar-Apr 4
19 8268852 Cytochrome P450 isozymes catalyzing the hepatic microsomal oxidation of 9-anthraldehyde to 9-anthracene carboxylic acid in adult male rats. Biol Pharm Bull 1993 Sep 2
20 8423554 Species differences in stereoselective metabolism of mephenytoin by cytochrome P450 (CYP2C and CYP3A). J Pharmacol Exp Ther 1993 Jan 2
21 8531135 Inhibition of the rat cytochrome P450 3A2 by an antisense phosphorothioate oligodeoxynucleotide in vivo. J Pharmacol Exp Ther 1995 Dec 2
22 8535396 Cytochrome P450 isozymes involved in aromatic hydroxylation and side-chain N-desisopropylation of alprenolol in rat liver microsomes. Biol Pharm Bull 1995 Aug 2
23 8573203 Impact of tamoxifen on peripubertal androgen imprinting of rat hepatic cytochrome P450 2C11, cytochrome P450 3A2, and steroid 5 alpha-reductase. Biochem Pharmacol 1996 Feb 9 1
24 8577819 Depletion of cytochrome P-450 by thyroid hormone and cobalt-protoporphyrin IX in rat liver: evidence that susceptibility varies among forms of the heme protein. Pharmacology 1995 Oct 4
25 8625305 Oltipraz-mediated changes in aflatoxin B(1) biotransformation in rat liver: implications for human chemointervention. Cancer Res 1996 May 15 1
26 8690406 Interferon gamma down-regulates cytochrome P450 3A genes in primary cultures of well-differentiated rat hepatocytes. Hepatology 1996 Aug 1
27 8694846 Effects of metyrapone on expression of CYPs 2C11, 3A2, and other 3A genes in rat hepatocytes cultured on matrigel. Biochem Pharmacol 1996 Jul 26 5
28 8696774 Interaction of 2,4,4'-trichloro-2'-hydroxydiphenyl ether with microsomal cytochrome P450-dependent monooxygenases in rat liver. Chemosphere 1996 Jul 2
29 8849332 Distribution and induction of CYP3A1 and CYP3A2 in rat liver and extrahepatic tissues. Biochem Pharmacol 1995 Dec 22 2
30 8865369 Trimethadione N-demethylation by rat liver CYP2E1 in vitro. Res Commun Mol Pathol Pharmacol 1996 Jul 1
31 8866826 Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat. Biochem Pharmacol 1996 Apr 26 1
32 8879146 Nefiracetam hydroxylation by rat liver microsomes and expressed human cytochrome P450s. Xenobiotica 1996 Aug 1
33 8886602 Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. Drug Metab Dispos 1996 Sep 1
34 8894516 Fluoroquinolone antibiotics inhibit cytochrome P450-mediated microsomal drug metabolism in rat and human. Drug Metab Dispos 1996 Oct 2
35 8968370 Enhanced inhibition of microsomal cytochrome P450 3A2 in rat liver during diltiazem biotransformation. J Pharmacol Exp Ther 1996 Dec 6
36 9193873 Cytochrome P450 responsible for the stereoselective S-oxidation of flosequinan in hepatic microsomes from rats and humans. Drug Metab Dispos 1997 Jun 7
37 9217276 Expression of cytochrome P450 isoforms in rat hepatic stellate cells. Life Sci 1997 2
38 9268688 Effect of vitamin A deficiency on the expression of low affinity glucocorticoid binding site activity and glucocorticoid-dependent induction of CYP3A2 in rat liver. Biochem Biophys Res Commun 1997 Aug 18 5
39 9321518 Mechanism of cytochrome P450 activation by caffeine and 7,8-benzoflavone in rat liver microsomes. Drug Metab Dispos 1997 Oct 2
40 9353139 Developmental changes in the constitutive and inducible expression of cytochrome P450 3A2. Biochem Pharmacol 1997 Oct 1 3
41 9399990 The In vitro hepatic metabolism of quinine in mice, rats and dogs: comparison with human liver microsomes. J Pharmacol Exp Ther 1997 Dec 1
42 9443857 Ethosuximide is primarily metabolized by CYP3A when incubated with isolated rat liver microsomes. Drug Metab Dispos 1998 Jan 2
43 9458185 Changes in cytochrome P450 enzymes by 1,1-dichloroethylene in rat liver and kidney. Arch Toxicol 1997 1
44 9493318 Changes in hepatic cytochrome P450 enzymes by cis- and trans-1,2-dichloroethylenes in rat. Xenobiotica 1998 Jan 3
45 9569940 Effect of 2,4,4'-trichloro-2'-hydroxydiphenyl ether on cytochrome P450 enzymes in the rat liver. Chemosphere 1997 Feb 2
46 9708877 Suppression of male-specific cytochrome P450 isoforms by bisphenol A in rat liver. Arch Toxicol 1998 Jun 6
47 9717516 Comparative induction of CYP3A and CYP2B in rat liver by 3-benzoylpyridine and metyrapone. Chem Biol Interact 1998 Jun 5 1
48 9806224 Effects of glucocorticoids on pharmacokinetics and pharmacodynamics of midazolam in rats. Life Sci 1998 4
49 9870717 Reduction of thyroid hormone may participate in the modulation of cytochromes P450 2C11 and 3A2 by retinol. Life Sci 1998 1
50 9890448 Identification of the cytochrome P450 isoenzymes involved in the metabolism of diazinon in the rat liver. J Biochem Mol Toxicol 1999 6