| Protein Name | Harvey rat sarcoma virus oncogene |
|---|---|
| Organism | Mus musculus |
| Gene ID | 15461 |
| Gene Symbol | Hras |
| UniProt | Q61411 (RASH_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
366
Total Number of Articles : 484 |
Description |
Harvey rat sarcoma virus oncogene |
| Gene Summary |
Enables GTP binding activity and membrane-membrane adaptor activity. Involved in several processes, including Ras protein signal transduction; insulin receptor signaling pathway; and nervous system development. Acts upstream of or within several processes, including defense response to protozoan; intracellular signal transduction; and oncogene-induced cell senescence. Predicted to be located in several cellular components, including Golgi apparatus; ciliary basal body; and nucleoplasm. Predicted to be part of GTPase complex. Predicted to be active in glutamatergic synapse and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; early embryo; genitourinary system; and sensory organ. Used to study Costello syndrome; high grade glioma; and malignant astrocytoma. Human ortholog(s) of this gene implicated in several diseases, including Costello syndrome; autistic disorder; carcinoma (multiple); epidermal nevus; and large congenital melanocytic nevus. Orthologous to human HRAS (HRas proto-oncogene, GTPase). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |