Protein Name glutamine fructose-6-phosphate transaminase 1
Organism Rattus norvegicus
Gene ID 297417
Gene Symbol

Gfpt1

UniProt P82808 (GFPT1_RAT), A0A0G2KB56 (A0A0G2KB56_RAT)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 41
Description

glutamine fructose-6-phosphate transaminase 1

Gene Summary

Enables several functions, including amino acid binding activity; glutamine-fructose-6-phosphate transaminase (isomerizing) activity; and identical protein binding activity. Involved in several processes, including cellular response to insulin stimulus; glucosamine biosynthetic process; and negative regulation of glycogen biosynthetic process. Biomarker of familial hyperlipidemia and hyperinsulinism. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12 and obesity. Orthologous to human GFPT1 (glutamine--fructose-6-phosphate transaminase 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1
  • D-fructose-6-phosphate amidotransferase 1
  • GFAT 1
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Properties