| Protein Name | sex determining region Y |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6736 |
| Gene Symbol | SRY |
| UniProt | Q05066 (SRY_HUMAN), A7WPU8 (A7WPU8_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
153
Total Number of Articles : 258 |
Description |
sex determining region Y |
| Gene Summary |
This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), which initiates male sex determination. Mutations in this gene give rise to XY females with gonadal dysgenesis (Swyer syndrome); translocation of part of the Y chromosome containing this gene to the X chromosome causes XX male syndrome. [provided by RefSeq, Jul 2008] |
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