| Protein Name | sphingosine N-acyltransferase LAG1 |
|---|---|
| Organism | Saccharomyces cerevisiae S288C |
| Gene ID | 856386 |
| Gene Symbol | LAG1 |
| UniProt | P38703 (LAG1_YEAST) |
| Relationships |
Total Number of functionally related compound(s) :
20
Total Number of Articles : 16 |
Description |
sphingosine N-acyltransferase LAG1 |
| Gene Summary |
Enables sphingosine N-acyltransferase activity. Involved in ceramide biosynthetic process. Located in endoplasmic reticulum. Part of acyl-CoA ceramide synthase complex. Used to study hepatocellular carcinoma; steatotic liver disease; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Orthologous to several human genes including CERS2 (ceramide synthase 2); CERS4 (ceramide synthase 4); and CERS6 (ceramide synthase 6). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |