sphingosine N-acyltransferase LAG1 ; Saccharomyces cerevisiae S288C






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1 11387200 C26-CoA-dependent ceramide synthesis of Saccharomyces cerevisiae is operated by Lag1p and Lac1p. EMBO J 2001 Jun 1 11
2 11694577 Lag1p and Lac1p are essential for the Acyl-CoA-dependent ceramide synthase reaction in Saccharomyces cerevisae. Mol Biol Cell 2001 Nov 7
3 12105227 Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J Biol Chem 2002 Sep 20 9
4 12200041 LAG1 puts the focus on ceramide signaling. Int J Biochem Cell Biol 2002 Nov 5
5 12869556 Human homologues of LAG1 reconstitute Acyl-CoA-dependent ceramide synthesis in yeast. J Biol Chem 2003 Sep 26 1
6 15236759 Suppressor analysis points to the subtle role of the LAG1 ceramide synthase gene in determining yeast longevity. Exp Gerontol 2004 Jul 1
7 16303764 The CLN9 protein, a regulator of dihydroceramide synthase. J Biol Chem 2006 Feb 3 1
8 16756512 Transmembrane topology of ceramide synthase in yeast. Biochem J 2006 Sep 15 2
9 16987101 Yeast sphingolipids do not need to contain very long chain fatty acids. Biochem J 2007 Jan 1 2
10 20208441 Effect of expression of genes in the sphingolipid synthesis pathway on the biosynthesis of ceramide in Saccharomyces cerevisiae. J Microbiol Biotechnol 2010 Feb 1
11 22211636 Distinct roles of two ceramide synthases, CaLag1p and CaLac1p, in the morphogenesis of Candida albicans. Mol Microbiol 2012 Feb 1
12 23226203 Modulation of mitochondrial outer membrane permeabilization and apoptosis by ceramide metabolism. PLoS One 2012 2
13 23472095 Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK. PLoS One 2013 3
14 26752183 Functions of Ceramide Synthase Paralogs YPR114w and YJR116w of Saccharomyces cerevisiae. PLoS One 2016 7
15 31164445 Yeast ceramide synthases, Lag1 and Lac1, have distinct substrate specificity. J Cell Sci 2019 Jun 24 3
16 34492164 Regulation of sphingolipid biosynthesis in the endoplasmic reticulum via signals from the plasma membrane in budding yeast. FEBS J 2022 Jan 1