Protein Name aldehyde dehydrogenase 1 family member L1
Organism Homo sapiens
Gene ID 10840
Gene Symbol

ALDH1L1

UniProt O75891 (AL1L1_HUMAN), Q53H87 (Q53H87_HUMAN)
Relationships Total Number of functionally related compound(s) : 106
Total Number of Articles : 89
Description

aldehyde dehydrogenase 1 family member L1

Gene Summary

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

synonyms
  • cytosolic 10-formyltetrahydrofolate dehydrogenase
  • 10-formyltetrahydrofolate dehydrogenase
  • MER57B-ALDH1L1
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Properties