aldehyde dehydrogenase 1 family member L1 ; Homo sapiens






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1 2733692 Studies on the mechanism of methanol poisoning: purification and comparison of rat and human liver 10-formyltetrahydrofolate dehydrogenase. Mol Pharmacol 1989 Jun 1
2 3574297 Studies on the role of folic acid and folate-dependent enzymes in human methanol poisoning. Mol Pharmacol 1987 May 2
3 8975761 Folate and 10-formyltetrahydrofolate dehydrogenase in human and rat retina: relation to methanol toxicity. Toxicol Appl Pharmacol 1996 Dec 2
4 10395731 A noncatalytic tetrahydrofolate tight binding site is on the small domain of 10-formyltetrahydrofolate dehydrogenase. Arch Biochem Biophys 1999 Jul 15 2
5 10514998 A simple assay for formate dehydrogenase activity by gas chromatography-mass spectrometry. J Chromatogr A 1999 Sep 3 2
6 10585460 Aspartate 142 is involved in both hydrolase and dehydrogenase catalytic centers of 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 1999 Dec 10 14
7 10699858 Continuous enzymatic transformation in an enzyme membrane reactor with simultaneous NAD(H) regeneration. Reprinted from Biotechnology and Bioengineering, Vol. XXIII, No. 12, Pages 2789-2802 (1981). Biotechnol Bioeng 2000 Mar 20 2
8 11320079 On the role of conserved histidine 106 in 10-formyltetrahydrofolate dehydrogenase catalysis: connection between hydrolase and dehydrogenase mechanisms. J Biol Chem 2001 Jun 29 23
9 12684508 Disruption of a calmodulin central helix-like region of 10-formyltetrahydrofolate dehydrogenase impairs its dehydrogenase activity by uncoupling the functional domains. J Biol Chem 2003 Jun 20 2
10 12805405 Ectopic expression of 10-formyltetrahydrofolate dehydrogenase in A549 cells induces G1 cell cycle arrest and apoptosis. Mol Cancer Res 2003 Jun 3
11 12898106 An integrated electrochemical fructose biosensor based on tetrathiafulvalene-modified self-assembled monolayers on gold electrodes. Anal Bioanal Chem 2003 Oct 7
12 16014005 Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression. Biochem J 2005 Nov 1 4
13 16529396 Stabilization of a formate dehydrogenase by covalent immobilization on highly activated glyoxyl-agarose supports. Biomacromolecules 2006 Mar 2
14 16597835 Modular organization of FDH: Exploring the basis of hydrolase catalysis. Protein Sci 2006 May 10
15 16627483 Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 2006 Jul 7 41
16 16712799 Leucovorin-induced resistance against FDH growth suppressor effects occurs through DHFR up-regulation. Biochem Pharmacol 2006 Jul 14 12
17 17111379 The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol 2007 Jan 10 1
18 17525747 Cooperation between JNK1 and JNK2 in activation of p53 apoptotic pathway. Oncogene 2007 Nov 8 1
19 18031047 Stereocomplementary bioreduction of alpha,beta-unsaturated dicarboxylic acids and dimethyl esters using enoate reductases: enzyme- and substrate-based stereocontrol. Org Lett 2007 Dec 20 1
20 18201543 Bienzyme amperometric biosensor using gold nanoparticle-modified electrodes for the determination of inulin in foods. Anal Biochem 2008 Apr 15 4
21 18555296 Coimmobilization of malate dehydrogenase and formate dehydrogenase in polyethyleneglycol(#4000)diacrylate gel by droplet gel-entrapping method. Biotechnol Bioeng 1986 Dec 5
22 18581429 Affinity partitioning: Development of mathematical model describing behavior of biomolecules in aqueous two-phase systems. Biotechnol Bioeng 1987 Sep 3
23 18646819 A theoretical study of the catalytic mechanism of formate dehydrogenase. J Phys Chem B 2008 Aug 14 6
24 18848533 FDH: an aldehyde dehydrogenase fusion enzyme in folate metabolism. Chem Biol Interact 2009 Mar 16 17
25 19147541 10-formyltetrahydrofolate dehydrogenase-induced c-Jun-NH2-kinase pathways diverge at the c-Jun-NH2-kinase substrate level in cells with different p53 status. Mol Cancer Res 2009 Jan 5
26 19244382 Production of 1-carbon units from glycine is extensive in healthy men and women. J Nutr 2009 Apr 2
27 19933275 Acyl carrier protein-specific 4'-phosphopantetheinyl transferase activates 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 2010 Jan 15 7
28 20498374 ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase. J Biol Chem 2010 Jul 23 2
29 20630178 Amperometric sensor for cyanide utilizing cyanidase and formate dehydrogenase. Anal Chim Acta 2010 Jul 12 3
30 20715198 Do dynamic effects play a significant role in enzymatic catalysis? A theoretical analysis of formate dehydrogenase. Chemistry 2010 Oct 4 6
31 20729910 ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A. Oncogene 2010 Nov 25 2
32 21391588 Self-regulating enzyme-nanotube ensemble films and their application as flexible electrodes for biofuel cells. J Am Chem Soc 2011 Apr 6 2
33 21540484 Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme. J Biol Chem 2011 Jul 1 6
34 21779486 Epigenetic Silencing of ALDH1L1, a Metabolic Regulator of Cellular Proliferation, in Cancers. Genes Cancer 2011 Feb 3
35 21806784 The respiratory molybdo-selenoprotein formate dehydrogenases of Escherichia coli have hydrogen: benzyl viologen oxidoreductase activity. BMC Microbiol 2011 Aug 1 14
36 22099650 Modified gold surfaces by poly(amidoamine) dendrimers and fructose dehydrogenase for mediated fructose sensing. Talanta 2011 Dec 15 7
37 22100631 Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis. Med Hypotheses 2012 Feb 4
38 22126535 3-picolyl azide adenine dinucleotide as a probe of femtosecond to picosecond enzyme dynamics. J Phys Chem B 2012 Jan 12 2
39 22470981 Artificial leaf device for solar fuel production. Faraday Discuss 2012 2
40 22593801 Activation of p21-Dependent G1/G2 Arrest in the Absence of DNA Damage as an Antiapoptotic Response to Metabolic Stress. Genes Cancer 2011 Sep 2
41 22917965 Micro-cubic monolithic carbon cryogel electrode for direct electron transfer reaction of fructose dehydrogenase. Bioelectrochemistry 2012 Dec 4
42 23295222 The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1. Chem Biol Interact 2013 Feb 25 7
43 23378610 Genetic variants associated with glycine metabolism and their role in insulin sensitivity and type 2 diabetes. Diabetes 2013 Jun 1
44 23519469 Folate stress induces apoptosis via p53-dependent de novo ceramide synthesis and up-regulation of ceramide synthase 6. J Biol Chem 2013 May 3 6
45 23692761 Rapid and direct determination of fructose in food: a new osmium-polymer mediated biosensor. Food Chem 2013 Oct 15 4
46 24320595 Automated workflow-based exploitation of pathway databases provides new insights into genetic associations of metabolite profiles. BMC Genomics 2013 Dec 9 4
47 24469104 Improvement of a direct electron transfer-type fructose/dioxygen biofuel cell with a substrate-modified biocathode. Phys Chem Chem Phys 2014 Mar 14 5
48 24651765 Genome-wide meta-analysis of homocysteine and methionine metabolism identifies five one carbon metabolism loci and a novel association of ALDH1L1 with ischemic stroke. PLoS Genet 2014 Mar 1
49 25304811 Screening aberrant methylation profile in esophageal squamous cell carcinoma for Kazakhs in Xinjiang area of China. Mol Biol Rep 2015 Feb 2
50 25512087 N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes. Chem Biol Interact 2015 Jun 5 1