| Protein Name | adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 290537 |
| Gene Symbol | Appl1 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
22
Total Number of Articles : 21 |
Description |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 |
| Gene Summary |
Predicted to enable several functions, including beta-tubulin binding activity; phospholipid binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including cell surface receptor signaling pathway; positive regulation of biosynthetic process; and regulation of endocytosis. Is active in postsynapse and presynapse. Human ortholog(s) of this gene implicated in maturity-onset diabetes of the young type 14. Orthologous to human APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |