Protein Name | U2 small nuclear RNA auxiliary factor 1 |
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Organism | Homo sapiens |
Gene ID | 7307 |
Gene Symbol | U2AF1 |
UniProt | Q01081 (U2AF1_HUMAN), P0DN76 (U2AF5_HUMAN), Q7Z780 (Q7Z780_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
24
Total Number of Articles : 30 |
Description |
U2 small nuclear RNA auxiliary factor 1 |
Gene Summary |
This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
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