U2 small nuclear RNA auxiliary factor 1 ; Homo sapiens






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1 1388271 Cloning and intracellular localization of the U2 small nuclear ribonucleoprotein auxiliary factor small subunit. Proc Natl Acad Sci U S A 1992 Sep 15 1
2 8816800 Mutations in the small subunit of the Drosophila U2AF splicing factor cause lethality and developmental defects. Proc Natl Acad Sci U S A 1996 Sep 17 2
3 9237760 A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA. Nature 1997 Jul 24 2
4 10567551 Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65). Mol Cell Biol 1999 Dec 1
5 10617206 Functional recognition of the 3' splice site AG by the splicing factor U2AF35. Nature 1999 Dec 16 1
6 10801464 Mechanisms of fidelity in pre-mRNA splicing. Curr Opin Cell Biol 2000 Jun 1
7 11118443 Nucleocytoplasmic shuttling of heterodimeric splicing factor U2AF. J Biol Chem 2001 Apr 20 2
8 11421359 The role of U2AF35 and U2AF65 in enhancer-dependent splicing. RNA 2001 Jun 2
9 11551507 A novel peptide recognition mode revealed by the X-ray structure of a core U2AF35/U2AF65 heterodimer. Cell 2001 Sep 7 2
10 11739736 Characterization of U2AF(6), a splicing factor related to U2AF(35). Mol Cell Biol 2002 Jan 4
11 16043505 FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35. RNA 2005 Aug 1
12 16809543 Intron removal requires proofreading of U2AF/3' splice site recognition by DEK. Science 2006 Jun 30 3
13 16940179 In vivo requirement of the small subunit of U2AF for recognition of a weak 3' splice site. Mol Cell Biol 2006 Nov 2
14 20831869 A disulfide driven domain swap switches off the activity of Shigella IpaH9.8 E3 ligase. FEBS Lett 2010 Oct 8 1
15 22158538 Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet 2011 Dec 11 3
16 25311244 U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing. Leukemia 2015 Apr 1
17 27419369 Somatic mutations predict outcomes of hypomethylating therapy in patients with myelodysplastic syndrome. Oncotarget 2016 Aug 23 1
18 27799531 Recognition of the 3' splice site RNA by the U2AF heterodimer involves a dynamic population shift. Proc Natl Acad Sci U S A 2016 Nov 15 2
19 28067246 Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome. Nat Commun 2017 Jan 9 1
20 28850223 Cancer-Associated Mutations Mapped on High-Resolution Structures of the U2AF2 RNA Recognition Motifs. Biochemistry 2017 Sep 12 1
21 30334576 Enasidenib-induced eosinophilic differentiation in a patient with acute myeloid leukaemia with IDH2 and U2AF1 mutations. Br J Haematol 2019 Feb 1
22 30693020 Widespread Separation of the Polypyrimidine Tract From 3' AG by G Tracts in Association With Alternative Exons in Metazoa and Plants. Front Genet 2018 1
23 31992135 Deoxynivalenol globally affects the selection of 3' splice sites in human cells by suppressing the splicing factors, U2AF1 and SF1. RNA Biol 2020 Apr 2
24 32343311 A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation. Nucleic Acids Res 2020 Jun 4 2
25 32778513 Retrospective Analysis of the Clinical Use and Benefit of Lenalidomide and Thalidomide in Myelofibrosis. Clin Lymphoma Myeloma Leuk 2020 Dec 1
26 32958768 Elucidation of the aberrant 3' splice site selection by cancer-associated mutations on the U2AF1. Nat Commun 2020 Sep 21 1
27 33330095 Lysine in Combination With Estradiol Promote Dissemination of Estrogen Receptor Positive Breast Cancer <i>via</i> Upregulation of U2AF1 and RPN2 Proteins. Front Oncol 2020 1
28 33477033 Down regulation of U2AF1 promotes ARV7 splicing and prostate cancer progression. Biochem Biophys Res Commun 2021 Feb 19 1
29 34893123 [Effect of U2AF1 Mutation to Inflammatory Cytokine Expression in SKM-1 Cells through FOXO3a-Bim Signaling Pathway]. Zhongguo Shi Yan Xue Ye Xue Za Zhi 2021 Dec 1
30 35434831 U2AF1 mutation connects DNA damage to the alternative splicing of RAD51 in lung adenocarcinomas. Clin Exp Pharmacol Physiol 2022 Jul 1