Protein Name Rho/Rac guanine nucleotide exchange factor 2
Organism Homo sapiens
Gene ID 9181
Gene Symbol

ARHGEF2

UniProt Q92974 (ARHG2_HUMAN), A0A5F9ZI21 (A0A5F9ZI21_HUMAN)
Relationships Total Number of functionally related compound(s) : 136
Total Number of Articles : 220
Description

Rho/Rac guanine nucleotide exchange factor 2

Gene Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]

synonyms
  • rho guanine nucleotide exchange factor 2
  • Rho/Rac guanine nucleotide exchange factor (GEF) 2
  • guanine nucleotide exchange factor H1
Click to show/hide the synonyms
Properties